SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation. (Q36383865)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

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title

SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

William R Heath

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

R Starr

series ordinal

3

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16 January 2020

publication date

1 January 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

number of pages

9

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based on heuristic

inferred from page(s)

published in

Tissue Antigens

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16 January 2020

volume

67

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16 January 2020

issue

1

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16 January 2020

page(s)

1-9

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A family of cytokine-inducible inhibitors of signalling

16 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

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Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

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Twenty proteins containing a C-terminal SOCS box form five structural classes

21 January 2018

1 reference

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Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation

21 January 2018

1 reference

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The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

21 January 2018

1 reference

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

1 reference

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The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

21 January 2018

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Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

21 January 2018

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

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Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

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IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma

21 January 2018

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Regulation of SOCS-1 expression by translational repression

21 January 2018

1 reference

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Pim serine/threonine kinases regulate the stability of Socs-1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Regulation of cytokine signaling by SOCS family molecules

21 January 2018

1 reference

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

21 January 2018

1 reference

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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

21 January 2018

1 reference

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

1 reference

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SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-gamma and lacking the SOCS-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo

21 January 2018

1 reference

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Suppressor of Cytokine Signaling-1 Has IFN- -Independent Actions in T Cell Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Target cell defense prevents the development of diabetes after viral infection.

21 January 2018

1 reference

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Suppressor of cytokine signaling gene expression in human pancreatic islets: modulation by cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Socs1 deficiency enhances hepatic insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

The tumor suppressor activity of SOCS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

21 January 2018

1 reference

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Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

Suppressor of cytokine signaling 1 attenuates IL-15 receptor signaling in CD8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2005.00532.X

10.1111/J.1399-0039.2005.00532.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16451196%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference