Informed conditioning on clinical covariates increases power in case-control association studies (Q36384402)

13 August 2017

Informed conditioning on clinical covariates increases power in case-control association studies (English)

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Loic Le Marchand

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Eric Tchetgen Tchetgen

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Eric Tchetgen Tchetgen

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Bogdan Pasaniuc

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Lynne J Hocking

Lynne J Hocking

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Angela Risch

Angela Risch

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John K. Field

John K Field

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Joachim Heinrich

Joachim Heinrich

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Heike Bickeböller

Heike Bickeböller

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Leif Groop

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Leif Groop

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Christopher A. Haiman

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Christopher Haiman

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Brian E Henderson

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David J Hunter

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Noah Zaitlen

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Benjamin Voight

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Daniel I Chasman

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Carl D Langefeld

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Barry I Freedman

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Donald W Bowden

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Nick Patterson

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David C Christiani

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Pamela J Hicks

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Robert M Plenge

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Paul Wordsworth

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Marilyn Cornelis

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Giulio Genovese

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Samuela Pollack

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Alkes L Price

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Laurence N Kolonel

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Maria Teresa Landi

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Ann W Morgan

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Anthony G Wilson

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Peter Kraft

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Sara Lindström

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Steve Eyre

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David J Friedman

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Aage Haugen

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Michael Meister

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Olaide Y Raji

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Albert Rosenberger

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David Scherf

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Sophia Steer

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Martin Walshaw

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Kevin M Waters

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Shanbeh Zienolddiny

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Debra A Schaumberg

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8 November 2012

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e1003032

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Creative Commons Attribution 4.0 International

13 August 2017

start time

8 November 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Analysis of case-control association studies with known risk variants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Estimating missing heritability for disease from genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Association of trypanolytic ApoL1 variants with kidney disease in African Americans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

New approaches to population stratification in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Gene--environment-wide association studies: emerging approaches

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

The genetic interpretation of area under the ROC curve in genomic profiling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Common variants at five new loci associated with early-onset inflammatory bowel disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Genome-wide association scans for secondary traits using case-control samples

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Diabetes prevalence and body mass index differ by ethnicity: the Multiethnic Cohort.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Power of deep, all-exon resequencing for discovery of human trait genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Data and theory point to mainly additive genetic variance for complex traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Rheumatoid arthritis association at 6q23.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A new multipoint method for genome-wide association studies by imputation of genotypes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Principal components analysis corrects for stratification in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

The importance of the normality assumption in large public health data sets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Mapping mendelian factors underlying quantitative traits using RFLP linkage maps

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Link functions in multi-locus genetic models: implications for testing, prediction, and interpretation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Identification of low-frequency variants associated with gout and serum uric acid levels

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

What's the best statistic for a simple test of genetic association in a case-control study?

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Improved power offered by a score test for linkage disequilibrium mapping of quantitative-trait loci by selective genotyping

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Including known covariates can reduce power to detect genetic effects in case-control studies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Chipping away at the genetics of smoking behavior.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A common variant at chromosome 9P21.3 is associated with age of onset of coronary disease but not subsequent mortality

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Simple optimal weighting of cases and controls in case-control studies.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

A candidate gene approach to searching for low-penetrance breast and prostate cancer genes

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003032

21 January 2018

When the smoke clears ..

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003032

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

The Liverpool Lung Project research protocol

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493452

Extreme discordant sib pairs for mapping quantitative trait loci in humans

5 December 2018

1 reference

12 December 2020

Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies

1 reference

12 December 2020

Cigarette smoking: an epidemiological overview

1 reference

12 December 2020

A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors

1 reference

12 December 2020

Exploiting gene-environment interaction to detect genetic associations

1 reference

12 December 2020

Power of selective genotyping in genetic association analyses of quantitative traits

1 reference

12 December 2020

The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1003032

Identifiers

DOI

1 reference

13 August 2017

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13 August 2017

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