The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion. (Q36387165)

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English	The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.	scientific article

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1 March 2020

The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion (English)

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1 March 2020

Toxoplasma gondii

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1 March 2020

Lara Mittereder

2

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1 March 2020

Thomas B Nutman

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1 March 2020

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1 March 2020

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Alan Sher

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1 March 2020

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Sandra Bonne-Annee

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1 March 2020

Sara Hieny

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1 March 2020

Dragana Jankovic

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23 November 2015

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1 March 2020

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12

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685007

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21 March 2022

Journal of Immunology

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196

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1 March 2020

1

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1 March 2020

345-356

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1 March 2020

The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria

1 reference

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Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii

1 reference

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30 September 2017

Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis

1 reference

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30 September 2017

Toxoplasma gondii- derived profilin triggers human toll-like receptor 5-dependent cytokine production

1 reference

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Nerve growth factor downregulates inflammatory response in human monocytes through TrkA

1 reference

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30 September 2017

Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men.

1 reference

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Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse

1 reference

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30 September 2017

Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.

1 reference

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Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

1 reference

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Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii

1 reference

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NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection

1 reference

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CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites

1 reference

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1 reference

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Technical advance: Caspase-1 activation and IL-1β release correlate with the degree of lysosome damage, as illustrated by a novel imaging method to quantify phagolysosome damage.

1 reference

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1 reference

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30 September 2017

Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions

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Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice

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Comparison of gene expression profiles between human and mouse monocyte subsets

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30 September 2017

4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion

1 reference

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Toxoplasmosis: A history of clinical observations

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Blood monocytes: development, heterogeneity, and relationship with dendritic cells

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Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

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Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

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30 September 2017

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30 September 2017

Pulling together: an integrated model of Toxoplasma cell invasion

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The evolution of vertebrate Toll-like receptors

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30 September 2017

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

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Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells.

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30 September 2017

Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens

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Toxoplasma gondii: transmission, diagnosis and prevention

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Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production

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Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T ce

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28 June 2018

Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

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28 June 2018

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

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Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

1 reference

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21 September 2018

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype.

1 reference

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21 September 2018

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

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Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26597011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients

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https://pubmed.ncbi.nlm.nih.gov/26597011

12 December 2020

based on heuristic

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Identifiers

10.4049/JIMMUNOL.1501558

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1 March 2020

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Europe PubMed Central

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1 March 2020

1 reference

Europe PubMed Central

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1 March 2020

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