A simple mechanistic explanation for original antigenic sin and its alleviation by adjuvants (Q36389642)

13 August 2017

A simple mechanistic explanation for original antigenic sin and its alleviation by adjuvants (English)

1 reference

13 August 2017

1

Wilfred Ndifon

1 reference

13 August 2017

1 November 2015

1 reference

Journal of the Royal Society Interface

13 August 2017

1 reference

13 August 2017

12

1 reference

13 August 2017

112

1 reference

Impact of repeated vaccination on vaccine effectiveness against influenza A(H3N2) and B during 8 seasons

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Influenza vaccine effectiveness in the 2011-2012 season: protection against each circulating virus and the effect of prior vaccination on estimates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Cutting edge: Heterosubtypic influenza infection antagonizes elicitation of immunological reactivity to hemagglutinin.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Chromatin conformation governs T-cell receptor Jβ gene segment usage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Strategies to alleviate original antigenic sin responses to influenza viruses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Understanding original antigenic sin in influenza with a dynamical system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Original antigenic sin responses to influenza viruses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Mechanisms of foxp3+ T regulatory cell-mediated suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

On the use of hemagglutination-inhibition for influenza surveillance: surveillance data are predictive of influenza vaccine effectiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

The who, how and where of antigen presentation to B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Variable efficacy of repeated annual influenza vaccination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Resting memory CD8+ T cells are hyperreactive to antigenic challenge in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

T cell activation determined by T cell receptor number and tunable thresholds.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Disquisitions on Original Antigenic Sin. II. Proof in lower creatures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Influenza Virus Subunit Vaccines. II. Immunogenicity and Original Antigenic Sin in Humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Regulatory and effector T cell activation levels are prime determinants of in vivo immune regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Epidemiologic and immunologic significance of age distribution of antibody to antigenic variants of influenza virus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Original antigenic sin at the cellular level. I. Antibodies produced by individual cells against cross-reacting haptens.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4685838

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSIF.2015.0627

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSIF.2015.0627

Antigen-specific interaction between T and B cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSIF.2015.0627

Inducing and expanding regulatory T cell populations by foreign antigen

21 January 2018

1 reference

12 December 2020

Sequence space localization in the immune system response to vaccination and disease

1 reference

12 December 2020

Regulatory T cells dynamically control the primary immune response to foreign antigen

1 reference

12 December 2020

Experience with Vaccination Against Influenza in the Spring of 1947: A Preliminary Report

1 reference

12 December 2020

High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSIF.2015.0627

1 reference

13 August 2017

1 reference

PMC publication ID

4685838

13 August 2017

PubMed publication ID

26577593

1 reference

PMC publication ID

4685838