Growth factor signalling in prostatic growth: significance in tumour development and therapeutic targeting (Q36390245)

13 August 2017

1 reference

title

Growth factor signalling in prostatic growth: significance in tumour development and therapeutic targeting (English)

1 reference

13 August 2017

Arich Ryan Reynolds

1

1 reference

13 August 2017

Natasha Kyprianou

series ordinal

2

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 February 2006

1 reference

British Journal of Pharmacology

13 August 2017

1 reference

13 August 2017

147 Suppl 2

1 reference

13 August 2017

S144-52

1 reference

Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis?

30 September 2017

1 reference

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Specificity and versatility in tgf-beta signaling through Smads

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Endogenous inhibitors of angiogenesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Antagonists of growth hormone releasing hormone (GHRH) and of bombesin/gastrin releasing peptide (BN/GRP) suppress the expression of VEGF, bFGF, and receptors of the EGF/HER family in PC-3 and DU-145 human androgen-independent prostate cancers.

30 September 2017

1 reference

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

30 September 2017

1 reference

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Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Angiogenesis-targeted therapies in prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

IGF-binding proteins mediate TGF-beta 1-induced apoptosis in bovine mammary epithelial BME-UV1 cells.

30 September 2017

1 reference

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Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation

30 September 2017

1 reference

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Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion

30 September 2017

1 reference

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The role of alpha-blockers in the management of prostate cancer

30 September 2017

1 reference

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Promotion and attenuation of FGF signaling through the Ras-MAPK pathway

30 September 2017

1 reference

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Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression

30 September 2017

1 reference

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Apoptotic impact of alpha1-blockers on prostate cancer growth: a myth or an inviting reality?

30 September 2017

1 reference

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Novel targeting of apoptosis pathways for prostate cancer therapy

30 September 2017

1 reference

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

30 September 2017

1 reference

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Regulation of rat prostate stromal cell myodifferentiation by androgen and TGF-beta1.

30 September 2017

1 reference

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The IGF‐1 receptor in cancer biology

30 September 2017

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Targeting HIF-1 for cancer therapy

30 September 2017

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PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

30 September 2017

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Endocrine/paracrine/autocrine survival factor activity of bone microenvironment participates in the development of androgen ablation and chemotherapy refractoriness of prostate cancer metastasis in skeleton.

30 September 2017

1 reference

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The biology of VEGF and its receptors

30 September 2017

1 reference

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FGF8 isoform b expression in human prostate cancer

30 September 2017

1 reference

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Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction

30 September 2017

1 reference

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TGF-betal/Smad signaling in prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

The role of the IGF system in cancer: from basic to clinical studies and clinical applications

30 September 2017

1 reference

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PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis

30 September 2017

1 reference

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Signal transduction to hypoxia-inducible factor 1

30 September 2017

1 reference

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

30 September 2017

1 reference

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A potential autocrine role for vascular endothelial growth factor in prostate cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

30 September 2017

1 reference

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase

30 September 2017

1 reference

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Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Analysis of proteins and proteomes by mass spectrometry

30 September 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Fibroblast growth factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

The integrin-linked kinase (ILK) suppresses anoikis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Oleandrin suppresses activation of nuclear transcription factor-kappaB, activator protein-1, and c-Jun NH2-terminal kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis

30 September 2017

1 reference

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Androgen influences transforming growth factor-beta1 gene expression in human adrenocortical cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Dysregulated expression of growth factors and their receptors in the development of prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Decreased Src tyrosine kinase activity inhibits malignant human ovarian cancer tumor growth in a nude mouse model.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Transforming growth factor-beta in benign and malignant prostate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Diversity does make a difference: fibroblast growth factor-heparin interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

TGF-beta signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study

30 September 2017

1 reference

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Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Angiogenesis and prostate cancer: in vivo and in vitro expression of angiogenesis factors by prostate cancer cells

30 September 2017

1 reference

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V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

30 September 2017

1 reference

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Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia

30 September 2017

1 reference

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Alpha adrenoceptor blockade in the treatment of benign prostatic hyperplasia: past, present and future

30 September 2017

1 reference

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Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines

30 September 2017

1 reference

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Bone metastases: improving the therapeutic index

30 September 2017

1 reference

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Role of androgens in prostatic cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

30 September 2017

1 reference

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Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

30 September 2017

1 reference

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Diverse forms of a receptor for acidic and basic fibroblast growth factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Transforming growth factor-beta.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Bcl-2 antagonizes the combined apoptotic effect of transforming growth factor-beta and dihydrotestosterone in prostate cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Expression of vascular endothelial growth factor receptors in human prostate cancer

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751493

Incidence of apoptosis and cell proliferation in prostate cancer: relationship with TGF-beta1 and bcl-2 expression

28 June 2018

1 reference

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28 June 2018

1 reference

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21 September 2018

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21 September 2018

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Quinazoline-derived alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via an alpha1-adrenoceptor-independent action.

21 September 2018

1 reference

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Effect of epristeride on the expression of IGF-1 and TGF-beta receptors in androgen-induced castrated rat prostate.

21 September 2018

1 reference

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21 September 2018

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Expression of fibroblast growth factors (FGFs) and FGF receptors in human prostate

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Down-regulation of protein and mRNA expression for transforming growth factor-beta (TGF-beta1) type I and type II receptors in human prostate cancer

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Basic fibroblast growth factor levels in cancer cells and in sera of patients suffering from proliferative disorders of the prostate

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Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in normal and malignant human prostate

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Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue

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Early castration-induced upregulation of transforming growth factor beta1 and its receptors is associated with tumor cell apoptosis and a major decline in serum prostate-specific antigen in prostate cancer patients

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FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferation

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High levels of circulating insulin-like growth factor-I increase prostate cancer risk: a prospective study in a population-based nonscreened cohort

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Heparin protects basic and acidic FGF from inactivation

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Expression of basic fibroblast growth factor mRNA in benign prostatic hyperplasia and prostatic carcinoma

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Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium

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Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells

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12 December 2020

Insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in benign prostatic hyperplasia and prostate cancer

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Vascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: evidence for androgen dependent destabilization of vascular endothelial growth factor transcripts

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Insulin-like growth factors and prostate cancer

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Transforming growth factor beta and prostate cancer.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0706635

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJP.0706635

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

16465179

1 reference