Significant differences in cell-cell fusion and viral entry between strains revealed by scanning mutagenesis of the C-heptad repeat of HIV gp41 (Q36390483)

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English	Significant differences in cell-cell fusion and viral entry between strains revealed by scanning mutagenesis of the C-heptad repeat of HIV gp41	scientific article

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scholarly article

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29 February 2020

Significant differences in cell-cell fusion and viral entry between strains revealed by scanning mutagenesis of the C-heptad repeat of HIV gp41 (English)

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29 February 2020

membrane fusion involved in viral entry into host cell

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3

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29 February 2020

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Barbara Diaz-Aguilar

1

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29 February 2020

Karen Dewispelaere

2

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29 February 2020

Amy Jacobs

4

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publication date

7 May 2013

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29 February 2020

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29 February 2020

52

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29 February 2020

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29 February 2020

3552-3563

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29 February 2020

Mutations of Gln64 in the HIV-1 gp41 N-terminal heptad repeat render viruses resistant to peptide HIV fusion inhibitors targeting the gp41 pocket

1 reference

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30 September 2017

Permanent inhibition of viral entry by covalent entrapment of HIV gp41 on the virus surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Enzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected

1 reference

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30 September 2017

Visualization of retrovirus uptake and delivery into acidic endosomes

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30 September 2017

Alanine scanning mutagenesis of HIV-1 gp41 heptad repeat 1: insight into the gp120-gp41 interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions

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30 September 2017

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Role of the HIV gp120 conserved domain 5 in processing and viral entry

1 reference

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30 September 2017

Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.

1 reference

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30 September 2017

Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes

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30 September 2017

Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein

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30 September 2017

Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion

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30 September 2017

Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Structure-function studies of the self-assembly domain of the human immunodeficiency virus type 1 transmembrane protein gp41.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

1 reference

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30 September 2017

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

1 reference

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30 September 2017

Atomic structure of a thermostable subdomain of HIV-1 gp41

1 reference

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30 September 2017

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype

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30 September 2017

Atomic structure of the ectodomain from HIV-1 gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686141

30 September 2017

Core structure of gp41 from the HIV envelope glycoprotein

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30 September 2017

Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein

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30 September 2017

Inhibition of HIV-1 infection by a fusion domain binding peptide from the HIV-1 envelope glycoprotein GP41

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30 September 2017

Resistance of a human serum-selected human immunodeficiency virus type 1 escape mutant to neutralization by CD4 binding site monoclonal antibodies is conferred by a single amino acid change in gp120.

1 reference

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30 September 2017

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

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30 September 2017

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates

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30 September 2017

Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity.

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30 September 2017

Identification of a cis-acting element in human immunodeficiency virus type 2 (HIV-2) that is responsive to the HIV-1 rev and human T-cell leukemia virus types I and II rex proteins

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30 September 2017

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition

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30 September 2017

Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism

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30 September 2017

A monoclonal antibody to the gp120-CD4 complex has differential effect on HIV-induced syncytium formation and viral infectivity

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30 September 2017

Inhibition of HIV-1 Env-Mediated Cell-Cell Fusion by Lectins, Peptide T-20, and Neutralizing Antibodies

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28 June 2018

HIV-1 inhibition by a peptide

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28 June 2018

Synthetic peptides and anti-peptide antibodies as probes to study interdomain interactions involved in virus assembly: the envelope of the human immunodeficiency virus (HIV-1)

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28 June 2018

Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system

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21 September 2018

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

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21 September 2018

The inhibitory activity of an HIV type 1 peptide correlates with its ability to interact with a leucine zipper structure

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21 September 2018

Model for the structure of the HIV gp41 ectodomain: insight into the intermolecular interactions of the gp41 loop

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12 December 2020

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Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies

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12 December 2020

based on heuristic

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Thermostability of the HIV gp41 wild-type and loop mutations

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12 December 2020

based on heuristic

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Identifiers

10.1021/BI400201H

1 reference

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29 February 2020

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29 February 2020

1 reference

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29 February 2020

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