Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation (Q36399151)

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scientific article published on July 1, 1980

Language	Label	Description	Also known as
English	Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation	scientific article published on July 1, 1980

Statements

scholarly article

1 reference

Europe PubMed Central

14 August 2017

Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

M. S. Hershfield

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6254019

8 September 2023

N. M. Kredich

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6254019

8 September 2023

language of work or name

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publication date

1 July 1980

1 reference

Europe PubMed Central

14 August 2017

full work available at URL

https://europepmc.org/articles/PMC349819

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6254019

8 September 2023

https://europepmc.org/articles/PMC349819?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6254019

8 September 2023

https://pnas.org/doi/pdf/10.1073/pnas.77.7.4292

1 reference

10.1073/PNAS.77.7.4292

https://api.crossref.org/works/10.1073/PNAS.77.7.4292

8 September 2023

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

14 August 2017

77

1 reference

Europe PubMed Central

14 August 2017

7

1 reference

Europe PubMed Central

14 August 2017

4292-4296

1 reference

Europe PubMed Central

14 August 2017

The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

The effect of nucleosides and deoxycoformycin on adenosine and deoxyadenosine inhibition of human lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Differential sensitivity of human leukemic T cell lines and B cell lines to growth inhibition by deoxyadenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Overproduction of adenine deoxynucleosides and deoxynucletides in adenosine deaminase deficiency with severe combined immunodeficiency disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Deoxyadenosine metabolism and toxicity in cultured L5178Y cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

S -Adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Adenine and Adenosine Are Toxic to Human Lymphoblast Mutants Defective in Purine Salvage Enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Purine Synthesis and Excretion in Mutants of the WI-L2 Human Lymphoblastoid Line Deficient in Adenosine Kinase (AK) and Adenine Phosphoribosyltransferase (APRT)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

30 September 2017

Deoxycytidine kinase. II. Purification and general properties of the calf thymus enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

28 June 2018

Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

28 June 2018

Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

28 June 2018

Gene expression in synchronized lymphocytes: studies on the control of synthesis of immunoglobulin polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

28 June 2018

S-Adenosylhomocysteine Metabolism in Various Species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349819

28 June 2018

Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of de novo purine biosynthesis in human lymphoblasts. Coordinate control of proximal (rate-determining) steps and the inosinic acid branch point

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of S-adenosylhomocysteine in adenosine-mediated toxicity in cultured mouse T lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S-adenosylhomocysteine hydrolase is an adenosine-binding protein: a target for adenosine toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on a possible regulatory mechanism for the biosynthesis of deoxyribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the effect of some adenine derivatives on the incorporation in vitro of isotopically labelled compounds into the nucleic acids of Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further studies on the effect of deoxyadenosine on the accumulation of deoxyadenosine triphosphate and inhibition of deoxyribonucleic acid synthesis in Ehrlich ascites tumor cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/6254019

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.77.7.4292

1 reference

Europe PubMed Central

14 August 2017

1980PNAS...77.4292H

0 references

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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