Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells (Q36401236)

14 August 2017

Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells (English)

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14 August 2017

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G M Davey

1

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14 August 2017

S L Schober

2

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14 August 2017

B T Endrizzi

3

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14 August 2017

A K Dutcher

4

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14 August 2017

S C Jameson

5

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14 August 2017

K A Hogquist

6

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14 August 2017

language of work or name

English

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publication date

1 November 1998

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Journal of Experimental Medicine

14 August 2017

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14 August 2017

188

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14 August 2017

10

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14 August 2017

1867-1874

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Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

T cell positive selection by a high density, low affinity ligand

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

T cell antigen receptor signal transduction pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Partial signaling by CD8+ T cells in response to antagonist ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

T-cell-receptor affinity and thymocyte positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Changes at peptide residues buried in the major histocompatibility complex (MHC) class I binding cleft influence T cell recognition: a possible role for indirect conformational alterations in the MHC class I or bound peptide in determining T cell re

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

T cell receptor antagonist peptides induce positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

A differential-avidity model for T-cell selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Intracellular ionized calcium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Developmental regulation of TCR-CD3-dependent [Ca2+]i responses of individual normal and pp59fyn-deficient T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Positive selection of thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

The functional significance of two amino acid polymorphisms in the antigen-presenting domain of class I MHC molecules. Molecular dissection of Kbm3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Early deletion and late positive selection of T cells expressing a male-specific receptor in T-cell receptor transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

In vivo and in vitro clonal deletion of double-positive thymocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Limits to the differential avidity model of T cell selection in the thymus.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Mature T cell reactivity altered by peptide agonist that induces positive selection

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn).

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Evidence for a differential avidity model of T cell selection in the thymus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

CD69 expression during selection and maturation of CD4+8+ thymocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212399

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.188.10.1867

The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.188.10.1867

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.188.10.1867

Involvement of p21ras activation in T cell CD69 expression

21 January 2018

1 reference

12 December 2020

The 28-kDa/32-kDa activation antigen EA 1. Further characterization and signal requirements for its expression

1 reference

12 December 2020

Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4

1 reference

12 December 2020

Ligand thresholds at different stages of T cell development

1 reference

12 December 2020

T cell receptor alpha-chain pairing determines the specificity of residue 262 within the Kb-restricted, ovalbumin257-264 determinant

1 reference

12 December 2020

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

12 December 2020

Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice

1 reference

12 December 2020

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

1 reference

12 December 2020

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

12 December 2020

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

1 reference

12 December 2020

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

1 reference

12 December 2020

1 reference

12 December 2020

Development of peptide-selected CD8 T cells in fetal thymic organ culture occurs via the conventional pathway

1 reference

12 December 2020

Identification of a naturally occurring ligand for thymic positive selection

1 reference

12 December 2020

Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation

1 reference

12 December 2020

Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.188.10.1867

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

9815264

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