Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation (Q36403769)

14 August 2017

Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation (English)

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14 August 2017

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S Spiegelman

1

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14 August 2017

R Sawyer

2

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14 August 2017

R Nayak

3

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14 August 2017

E Ritzi

4

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14 August 2017

R Stolfi

5

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14 August 2017

D Martin

6

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14 August 2017

language of work or name

English

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publication date

1 August 1980

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

77

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14 August 2017

8

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14 August 2017

4966-4970

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Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

30 September 2017

An overview of thymidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Spontaneous murine mammary adenocarcinoma: model system for evaluation of combined methods of therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

30 September 2017

Fluorinated pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

In vivo enhancement of 5-fluorouracil cytotoxicity to AKR leukemia cells by thymidine in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Clinical, biological, and biochemical effect of pyrazofurin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Plasma levels of a viral protein as a diagnostic signal for the presence of mammary tumor: the effect of tumor removal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Plasma levels of a viral protein as a diagnostic signal for the presence of tumor : the murine mammary tumor model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

The purification of a gs antigen of the murine mammary tumor virus and its quantitation by radioimmunoassay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

The mechanism of 5-fluorouridine toxicity in Novikoff hepatoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Selective killing of transformed baby hamster kidney (BHK) cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

The inhibition of ribosomal RNA synthesis and maturation in Novikoff hepatoma cells by 5-fluorouridine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Transformation by polyoma virus alters expression of a cell mutation affecting cycle traverse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Biochemical aspects of chemotherapy of mouse colon carcinoma.Fluoropyrimidines and pyrazofurin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Initiation of DNA Synthesis by RNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Inhibition of Ribosomal Ribonucleic Acid Maturation in Rat Liver by 5-Fluoroorotic Acid Resulting in the Selective Labeling of Cytoplasmic Messenger Ribonucleic Acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

Studies on fluorinated pyrimidines. IX. The degradation of 5-fluorouracil-6-C14

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

The action of 5-fluorouracil on the nucleic acid metabolism of pseudorabies virus-infected and noninfected rabbit kidney cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=349970

RNA synthesis in the liver of rats treated with 5-fluorouracil

21 September 2018

1 reference

12 December 2020

Differential response of two derivatives of the BHK21 hamster cell to thymidine

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12 December 2020

Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine

1 reference

12 December 2020

5-Fluorouracil and derivatives in cancer chemotherapy. 3. In vivo enhancement of antitumor activity of 5-fluorouracil (FU) and 5-fluoro-2'-deoxyuridine (FUDR)

1 reference

12 December 2020

The effect of 5-fluorouracil on the synthesis of nuclear RNA in L1210 cells in vitro

1 reference

12 December 2020

In vivo potentiation of 5-fluorouracil cytotoxicity against AKR leukemia by purines, pyrimidines, and their nucleosides and deoxynucleosides

1 reference

12 December 2020

Potentiation of the anti-tumor activity of 5FU by thymidine and its correlation with the formation of (5FU)RNA

1 reference

12 December 2020

OETTGEN HF, REPPERT JA, COLEY V: Studies on the synergism of fluorinated pyrimidines and certain pyrimidine and purine derivatives against transplanted mouse leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.77.8.4966

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14 August 2017

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14 August 2017

PubMed publication ID

6933541

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