In silico toxicology models and databases as FDA Critical Path Initiative toolkits (Q36405302)

14 August 2017

2 references

14 September 2020

In silico toxicology models and databases as FDA Critical Path Initiative toolkits (English)

1 reference

14 August 2017

0 references

1 reference

14 September 2020

1 reference

Luis G Valerio

1

1 reference

14 August 2017

1 March 2011

2 references

14 August 2017

14 September 2020

2 references

14 August 2017

14 September 2020

5

1 reference

14 August 2017

3

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14 August 2017

200-207

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The in silico prediction of human-specific metabolites from hepatotoxic drugs

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

The computational prediction of genotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

A structural feature-based computational approach for toxicology predictions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Computational toxicology approaches at the US Food and Drug Administration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

The use of computer models in pharmaceutical safety evaluation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

The continuing evolution of torsades de pointes liability testing methods: is there an end in sight?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Computational toxicology--a tool for early safety evaluation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

In silico toxicology for the pharmaceutical sciences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

ICH S7B draft guideline on the non-clinical strategy for testing delayed cardiac repolarisation risk of drugs: a critical analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Drug-induced prolongation of the QT interval

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Testing computational toxicology models with phytochemicals.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Predictivity and reliability of QSAR models: the case of mutagens and carcinogens.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Phospholipidosis in neurons caused by posaconazole, without evidence for functional neurologic effects

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Current challenges in the evaluation of cardiac safety during drug development: translational medicine meets the Critical Path Initiative

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

28 June 2018

Dietary phytoestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

Computational science in drug metabolism and toxicology

28 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1479-7364-5-3-200

Successful virtual screening for a submicromolar antagonist of the neurokinin-1 receptor based on a ligand-supported homology model

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1479-7364-5-3-200

Is computational toxicology withering on the vine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1479-7364-5-3-200

Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1479-7364-5-3-200

Computational analysis for hepatic safety signals of constituents present in botanical extracts widely used by women in the United States for treatment of menopausal symptoms.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

International Conference on Harmonisation; guidance on E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs; availability. Notice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3500173

The trouble with QSAR (or how I learned to stop worrying and embrace fallacy)

21 September 2018

1 reference

12 December 2020

Early toxicity screening strategies

1 reference

12 December 2020

A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause

1 reference

12 December 2020

Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models

1 reference

12 December 2020

Tools for evidence-based toxicology: computational-based strategies as a viable modality for decision support in chemical safety evaluation and risk assessment

1 reference

12 December 2020

10.1186/1479-7364-5-3-200

Identifiers

DOI

1 reference

PMC publication ID

3500173

Dimensions Publication ID

14 August 2017

0 references

1 reference

PMC publication ID

3500173

14 August 2017

PubMed publication ID

21504870

1 reference

PMC publication ID

3500173