Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues (Q36410052)

14 August 2017

Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues (English)

1 reference

14 August 2017

G E Breitwieser

1

1 reference

PMCID

2216147

14 August 2017

G Szabo

series ordinal

2

1 reference

14 August 2017

1 April 1988

1 reference

The Journal of General Physiology

14 August 2017

1 reference

14 August 2017

91

1 reference

14 August 2017

4

1 reference

14 August 2017

469-493

1 reference

Acetylcholine-induced k current in amphibian atrial cells

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Heart muscle. Intracellular potassium and inward-going rectification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Distribution of muscarinic acetylcholine receptors and presynaptic nerve terminals in amphibian heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Ionic currents in single isolated bullfrog atrial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

G proteins: a family of signal transducers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Molecular properties of the muscarinic acetylcholine receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Signal transduction by guanine nucleotide binding proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The action of acetylcholine on background conductance in frog atrial trabeculae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

On the mechanism of activation of fat cell adenylate cyclase by guanine nucleotides. An explanation for the biphasic inhibitory and stimulatory effects of the nucleotides and the role of hormones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Synaptic delay in the heart: an ionophoretic study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Regulation of hormone-receptor coupling to adenylyl cyclase. Effects of GTP and GDP.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Involvement of a high-affinity GTPase in the inhibitory coupling of striatal muscarinic receptors to adenylate cyclase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Functional reconstitution of purified muscarinic receptors and inhibitory guanine nucleotide regulatory protein.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A novel holder allowing internal perfusion of patch-clamp pipettes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Comparison of steady-state electrophysiological properties of isolated cells from bullfrog atrium and sinus venosus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Functional interaction of purified muscarinic receptors with purified inhibitory guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Ciba-Geigy award for outstanding research. Regulation of adrenergic receptor function by phosphorylation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Activation of rat liver adenylate cyclase by guanosine 5'-[beta,gamma-imido]triphosphate and glucagon. Existence of reversibly and irreversibly activated states of the stimulatory GTP-binding protein

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Membrane currents and their modification by acetylcholine in isolated single atrial cells of the guinea-pig

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A quantitative analysis of the acetylcholine-activated potassium current in single cells from frog atrium.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

The alpha subunit of the GTP binding protein Gk opens atrial potassium channels.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Role of intracellular Mg2+ in the activation of muscarinic K+ channel in cardiac atrial cell membrane

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Acetylcholine activation of K+ channels in cell-free membrane of atrial cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Changes in membrane currents in bullfrog atrium produced by acetylcholine

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

Function of muscarinic and nicotinic acetylcholine receptors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

A kinetic model for the muscarinic action of acetylcholine.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

GTP-binding proteins couple cardiac muscarinic receptors to a K channel.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2216147

GTP hydrolysis by pure Ni, the inhibitory regulatory component of adenylyl cyclases

21 September 2018

1 reference

12 December 2020

Phorbol ester treatment impairs hormone- but not stable GTP analog-induced inhibition of adenylate cyclase

1 reference

12 December 2020

Transient and steady state kinetics of the interaction of guanyl nucleotides with the adenylyl cyclase system from rat liver plasma membranes. Interpretation in terms of a simple two-state model

1 reference

12 December 2020

ADP-ribosylation of Gs promotes the dissociation of its alpha and beta subunits

1 reference

12 December 2020

Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate

1 reference

12 December 2020

Ability of guanine nucleotide derivatives to bind and activate bovine transducin

1 reference

12 December 2020

Interaction of retinal transducin with guanosine triphosphate analogues: specificity of the gamma-phosphate binding region

1 reference

12 December 2020

Conditional inhibition of forskolin-activated adenylate cyclase by guanosine diphosphate and its analog

1 reference

12 December 2020

Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle

1 reference

12 December 2020

Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins

1 reference

12 December 2020

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions

1 reference

12 December 2020

Desensitization of the acetylcholine-induced increase of potassium conductance in rabbit cardiac Purkinje fibres

1 reference

12 December 2020

Effects of guanine nucleotides and Mg on human erythrocyte Ni and Ns, the regulatory components of adenylyl cyclase

1 reference

12 December 2020

Topology of the GTP-binding site of adenylyl cyclase from pigeon erythrocytes

1 reference

12 December 2020

Phosphorylation of the cardiac muscarinic receptor in intact chick heart and its regulation by a muscarinic agonist

1 reference

12 December 2020

Identifiers

DOI

10.1085/JGP.91.4.469

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

PMCID

2216147