Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction (Q36415327)

14 August 2017

Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction (English)

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14 August 2017

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Toshiaki Iba

1

1 reference

14 August 2017

Naoyuki Hashiguchi

2

1 reference

14 August 2017

Isao Nagaoka

3

1 reference

14 August 2017

Yoko Tabe

4

1 reference

14 August 2017

Katsuhiko Kadota

5

1 reference

14 August 2017

Koichi Sato

6

1 reference

14 August 2017

language of work or name

1 reference

29 December 2015

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Intensive care medicine experimental

14 August 2017

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14 August 2017

3

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14 August 2017

1

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14 August 2017

36

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Creative Commons Attribution 4.0 International

14 August 2017

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s40635-015-0072-z

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cites work

Heparin defends against the toxicity of circulating histones in sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Sepsis induces specific changes in histone modification patterns in human monocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Septic shock sera containing circulating histones induce dendritic cell-regulated necrosis in fatal septic shock patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Heparin therapy reduces 28-day mortality in adult severe sepsis patients: a systematic review and meta-analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Is the neutrophil a 'prima donna' in the procoagulant process during sepsis?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Anticoagulant therapy for sepsis-associated disseminated intravascular coagulation: the view from Japan

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Extracellular histones in tissue injury and inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

30 September 2017

Sepsis and thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Circulating histones are mediators of trauma-associated lung injury.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Results of a consensus meeting on the use of argatroban in patients with heparin-induced thrombocytopenia requiring antithrombotic therapy - a European Perspective

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Extracellular histones are major mediators of death in sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Sepsis, coagulation, and antithrombin: old lessons and new insights

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Neutrophils and immunity: challenges and opportunities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Neutrophil extracellular traps kill bacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Enoxaparin attenuates endothelial damage with less bleeding compared with unfractionated heparin in endotoxemic rats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Precipitation of fibrinogen, fibrinogen degradation products and fibrin monomer by histone H3.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Proteomic identification of interactions between histones and plasma proteins: implications for cytoprotection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Beneficial effect of clopidogrel in a mouse model of polymicrobial sepsis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

The effect of anticoagulants and the role of thrombin on neutrophil-endothelial cell interactions in septic shock

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695463

Prophylactic heparin in patients with severe sepsis treated with drotrecogin alfa (activated)

21 September 2018

1 reference

12 December 2020

Unfractioned heparin for treatment of sepsis: A randomized clinical trial (The HETRASE Study)

1 reference

12 December 2020

Heparin in plasma samples causes nonspecific binding to histones on Western blots

1 reference

12 December 2020

In vitro studies of a new synthetic thrombin inhibitor

1 reference

12 December 2020

10.1186/S40635-015-0072-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

14 August 2017

0 references

1 reference

14 August 2017

1 reference