Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs (Q36421684)

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English	Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs (English)

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Europe PubMed Central

PMC publication ID

14 August 2017

Alzheimer's disease

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transcriptomics

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inferred from title

Dmitry Velmeshev

2

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Dmitry Velmeshev

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Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Marco Magistri

1

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Europe PubMed Central

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14 August 2017

Madina Makhmutova

3

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Europe PubMed Central

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14 August 2017

Mohammad Ali Faghihi

4

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14 August 2017

publication date

3 September 2015

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Europe PubMed Central

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14 August 2017

Journal of Alzheimer's Disease

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Europe PubMed Central

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14 August 2017

48

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Europe PubMed Central

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14 August 2017

3

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Europe PubMed Central

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14 August 2017

647-665

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Europe PubMed Central

PMC publication ID

14 August 2017

A long noncoding RNA protects the heart from pathological hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1‑AS expression

1 reference

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30 September 2017

HuD regulates coding and noncoding RNA to induce APP→Aβ processing

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30 September 2017

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

1 reference

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30 September 2017

Blood-brain-barriers in aging and in Alzheimer's disease

1 reference

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30 September 2017

DNMT1-interacting RNAs block gene-specific DNA methylation

1 reference

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30 September 2017

Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders

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30 September 2017

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

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30 September 2017

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing.

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30 September 2017

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

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30 September 2017

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

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30 September 2017

Next-generation sequencing in understanding complex neurological disease

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30 September 2017

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

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30 September 2017

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

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30 September 2017

NCBI GEO: archive for functional genomics data sets--update

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30 September 2017

Long non-coding RNAs coordinate cellular responses to stress

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30 September 2017

Gene expression profiling in human neurodegenerative disease

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30 September 2017

Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

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30 September 2017

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Molecular mechanisms of long noncoding RNAs

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30 September 2017

lincRNAs act in the circuitry controlling pluripotency and differentiation

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30 September 2017

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

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30 September 2017

Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

The projected effect of risk factor reduction on Alzheimer's disease prevalence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Epigenetic mechanisms in Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

RNA sequencing: advances, challenges and opportunities

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30 September 2017

Understanding the pathogenesis of Alzheimer's disease: will RNA-Seq realize the promise of transcriptomics?

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30 September 2017

Long noncoding RNAs with enhancer-like function in human cells

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30 September 2017

Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions

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30 September 2017

Long noncoding RNA as modular scaffold of histone modification complexes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698155

30 September 2017

Small RNA-directed transcriptional control: new insights into mechanisms and therapeutic applications

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30 September 2017

Evidence for natural antisense transcript-mediated inhibition of microRNA function

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30 September 2017

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

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Widespread transcription at neuronal activity-regulated enhancers

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Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation

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The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease.

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12 December 2020

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