Cytotoxic activity of topotecan in human tumour cell lines and primary cultures of human tumour cells from patients (Q36422757)

14 August 2017

Cytotoxic activity of topotecan in human tumour cell lines and primary cultures of human tumour cells from patients (English)

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14 August 2017

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7

Larsson R

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14 August 2017

6

Nygren P

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14 August 2017

Jonsson E

1

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14 August 2017

Fridborg H

2

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14 August 2017

Csóka K

3

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14 August 2017

Dhar S

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14 August 2017

Sundström C

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14 August 2017

language of work or name

English

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publication date

1 January 1997

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British Journal of Cancer

14 August 2017

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14 August 2017

76

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14 August 2017

2

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14 August 2017

211-219

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https://scigraph.springernature.com/pub.10.1038/bjc.1997.364

14 August 2017

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cites work

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Drug resistance against gemcitabine and topotecan mediated by constitutive hsp70 overexpression in vitro: implication of quercetin as sensitiser in chemotherapy

30 September 2017

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Phase II study of topotecan in patients with advanced non-small-cell lung cancer previously untreated with chemotherapy

30 September 2017

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Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion

30 September 2017

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Cytotoxic drug sensitivity testing of tumor cells from patients with ovarian carcinoma using the fluorometric microculture cytotoxicity assay (FMCA).

30 September 2017

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

30 September 2017

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A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor topotecan (SK&F 104864) given as an intravenous bolus every 21 days

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

Development of vincristine resistance and increased sensitivity to cyclosporin A and verapamil in the human U-937 lymphoma cell line without overexpression of the 170-kDa P-glycoprotein

30 September 2017

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Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations

30 September 2017

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Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan

30 September 2017

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Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

30 September 2017

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Activity of 9-dimethylaminomethyl-10-hydroxycamptothecin against pediatric and adult central nervous system tumor xenografts

30 September 2017

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The cytotoxic activity of Taxol in primary cultures of tumour cells from patients is partly mediated by Cremophor EL.

28 June 2018

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Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.

28 June 2018

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Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors

28 June 2018

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Up-regulation of gamma-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

28 June 2018

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Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.

28 June 2018

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Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells

28 June 2018

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Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content

28 June 2018

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Verapamil and cyclosporin A sensitize human kidney tumor cells to vincristine in absence of membrane P-glycoprotein and without apparent changes in the cytoplasmic free Ca2+ concentration

28 June 2018

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Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors

28 June 2018

1 reference

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Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

In vitro and in vivo effects of clinically important camptothecin analogues on multidrug-resistant cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

In vitro activity of 2-chlorodeoxyadenosine (CdA) in primary cultures of human haematological and solid tumours.

21 September 2018

1 reference

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Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

In vitro and in vivo activity of topotecan against human B-lineage acute lymphoblastic leukemia cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223940

Cytotoxic activity of calcein acetoxymethyl ester (Calcein/AM) on primary cultures of human haematological and solid tumours

21 September 2018

1 reference

12 December 2020

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes)

1 reference

12 December 2020

Laboratory determination of chemotherapeutic drug resistance in tumor cells from patients with leukemia, using a fluorometric microculture cytotoxicity assay (FMCA)

1 reference

12 December 2020

Detection of tumor-specific cytotoxic drug activity in vitro using the fluorometric microculture cytotoxicity assay and primary cultures of tumor cells from patients

1 reference

12 December 2020

Phase II trial of topotecan in patients with advanced renal cell carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1997.364

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Dimensions Publication ID

14 August 2017

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1 reference

14 August 2017

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