Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP. (Q36430934)

14 August 2017

Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP. (English)

1 reference

14 August 2017

Bosanquet AG

1

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14 August 2017

Burlton AR

series ordinal

2

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14 August 2017

Bell PB

series ordinal

3

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14 August 2017

Harris AL

series ordinal

4

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14 August 2017

language of work or name

English

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publication date

1 January 1997

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British Journal of Cancer

14 August 2017

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14 August 2017

76

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14 August 2017

4

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14 August 2017

511-518

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https://scigraph.springernature.com/pub.10.1038/bjc.1997.417

14 August 2017

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Cancer chemotherapy: identifying novel anticancer drugs

30 September 2017

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A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group

30 September 2017

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The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional-related diseases

30 September 2017

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Transcriptional regulation of multidrug resistance in breast cancer

30 September 2017

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Prediction of drug resistance in cancer chemotherapy: the Kern and DiSC assays

30 September 2017

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Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3',5'-cyclic monophosphate

30 September 2017

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Reversal of resistance to adriamycin by 8-chloro-cyclic AMP in adriamycin-resistant HL-60 leukemia cells is associated with reduction of type I cyclic AMP-dependent protein kinase and cyclic AMP response element-binding protein DNA-binding activitie

30 September 2017

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8-Chloroadenosine mediates 8-chloro-cyclic AMP-induced down-regulation of cyclic AMP-dependent protein kinase in normal and neoplastic mouse lung epithelial cells by a cyclic AMP-independent mechanism

28 June 2018

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Evaluation of creatine analogues as a new class of anticancer agents using freshly explanted human tumor cells.

28 June 2018

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2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms

28 June 2018

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Methylprednisolone in advanced chronic lymphocytic leukaemia: rationale for, and effectiveness of treatment suggested by DiSC assay.

28 June 2018

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Overexpression of the RI alpha subunit of protein kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-chloro-cyclic adenosine 3'5'-monophosphate in Chinese hamster ovary cells

28 June 2018

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Pharmacokinetics of unchanged carboplatin (CBDCA) in patients with small cell lung carcinoma

28 June 2018

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28 June 2018

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8-Chloroadenosine 3',5'-monophosphate inhibits the growth of Chinese hamster ovary and Molt-4 cells through its adenosine metabolite

28 June 2018

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Correlations between therapeutic response of leukaemias and in-vitro drug-sensitivity assay

28 June 2018

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Growth inhibition of human glioma cells induced by 8-chloroadenosine, an active metabolite of 8-chloro cyclic adenosine 3':5'-monophosphate

28 June 2018

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Antineoplastic drug screening belongs in the laboratory, not in the clinic

28 June 2018

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8-Chloro-cyclic adenosine monophosphate, a novel cyclic AMP analog that inhibits human glioma cell growth in concentrations that do not induce differentiation

28 June 2018

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Alteration of type II regulatory subunit of cAMP-dependent protein kinase in human cisplatin-resistant cells as a basis of collateral sensitivity to 8-chloro-cAMP

28 June 2018

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In vitro activity of 2-chlorodeoxyadenosine (CdA) in primary cultures of human haematological and solid tumours.

28 June 2018

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Activity of NK 611, a new epipodophyllotoxin derivative, against colony forming units from freshly explanted human tumours in vitro.

21 September 2018

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Phase I clinical study with 8-chloro-cAMP and evaluation of immunological effects in cancer patients

21 September 2018

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Sensitive determination of 8-chloroadenosine 3',5'-monophosphate and 8-chloroadenosine in plasma by high-performance liquid chromatography

21 October 2018

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12 December 2020

Correlation of in vitro drug-sensitivity testing results with response to chemotherapy and survival in extensive-stage small cell lung cancer: a prospective clinical trial

1 reference

12 December 2020

Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) in patients with normal and impaired renal function

1 reference

12 December 2020

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12 December 2020

8-Cl-cAMP induces truncation and down-regulation of the RI alpha subunit and up-regulation of the RII beta subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells

1 reference

12 December 2020

Novel ex vivo analysis of nonclassical, pleiotropic drug resistance and collateral sensitivity induced by therapy provides a rationale for treatment strategies in chronic lymphocytic leukemia

1 reference

12 December 2020

Effects of 8-chloroadenosine-3',5'-monophosphate in combination with irradiation in L5178Y mouse lymphoblasts

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12 December 2020

Effects of 8-chloro-cyclic adenosine monophosphate on the growth and sensitivity to doxorubicin of multidrug-resistant tumour cell lines

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12 December 2020

Identifiers

DOI

10.1038/BJC.1997.417

1 reference

Dimensions Publication ID

14 August 2017

0 references

1 reference

14 August 2017

1 reference