Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models (Q36431788)

14 August 2017

Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models (English)

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5

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I G Obrosova

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V R Drel

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A K Kumagai

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C Szábo

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M J Stevens

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1 August 2006

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49

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2525-2533

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https://scigraph.springernature.com/pub.10.1007/s00125-006-0356-7

14 August 2017

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Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications

30 September 2017

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Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats

30 September 2017

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A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications

30 September 2017

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Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes

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Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy

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Retinal vascular changes induced by the oxidative stress of alpha-tocopherol deficiency contrasted with diabetic microangiopathy

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Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes.

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Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.

21 September 2018

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Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats

21 September 2018

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Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats

21 September 2018

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Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB.

21 September 2018

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Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

21 September 2018

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Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats

21 September 2018

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A central role for inflammation in the pathogenesis of diabetic retinopathy

21 September 2018

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Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

21 September 2018

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Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats

21 September 2018

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21 September 2018

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Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.

21 September 2018

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Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation

21 September 2018

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A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat.

21 September 2018

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Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes

21 September 2018

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Mechanisms of inhibitory activity of the aldose reductase inhibitor, epalrestat, on high glucose-mediated endothelial injury: neutrophil-endothelial cell adhesion and surface expression of endothelial adhesion molecules

21 September 2018

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Retinal metabolic abnormalities in diabetic mouse: comparison with diabetic rat.

21 September 2018

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Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat.

21 September 2018

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A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy

21 September 2018

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Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats

21 September 2018

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Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

21 September 2018

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Influence of tolrestat on the defective leukocyte-endothelial interaction in experimental diabetes

21 September 2018

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12 December 2020

Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid

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12 December 2020

Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia

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12 December 2020

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12 December 2020

Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats

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12 December 2020

Diabeteslike proliferative retinal changes in galactose-fed dogs

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12 December 2020

An aldose reductase inhibitor and aminoguanidine prevent vascular endothelial growth factor expression in rats with long-term galactosemia

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12 December 2020

Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor

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12 December 2020

Increased NADH oxidase activity in the retina of the BBZ/Wor diabetic rat

1 reference

12 December 2020

Dose-dependent reduction of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by the aldose reductase inhibitor M79175

1 reference

12 December 2020

Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lens

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12 December 2020

Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study

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12 December 2020

10.1007/S00125-006-0356-7

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DOI

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14 August 2017

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14 August 2017

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