The soluble form of BMPRIB is a novel therapeutic candidate for treating bone related disorders (Q36432535)

14 August 2017

The soluble form of BMPRIB is a novel therapeutic candidate for treating bone related disorders (English)

1 reference

14 August 2017

Kengo Yamawaki

1

1 reference

14 August 2017

Yuichiro Kondo

2

1 reference

14 August 2017

Tsutomu Okada

3

1 reference

14 August 2017

Takeshi Oshima

4

1 reference

14 August 2017

Makoto Kakitani

5

1 reference

14 August 2017

Kazuma Tomizuka

6

1 reference

14 August 2017

language of work or name

English

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publication date

6 January 2016

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14 August 2017

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14 August 2017

6

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14 August 2017

18849

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Creative Commons Attribution 4.0 International

14 August 2017

start time

6 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep18849

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cites work

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30 September 2017

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Adult-specific systemic over-expression reveals novel in vivo effects of the soluble forms of ActRIIA, ActRIIB and BMPRII.

30 September 2017

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BMP4 inhibits the proliferation of breast cancer cells and induces an MMP-dependent migratory phenotype in MDA-MB-231 cells in 3D environment

30 September 2017

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Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis

30 September 2017

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A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength

30 September 2017

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Bone morphogenetic proteins: a critical review

30 September 2017

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30 September 2017

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A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health

30 September 2017

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30 September 2017

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Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

30 September 2017

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BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury

30 September 2017

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ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth

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Sagopilone inhibits breast cancer bone metastasis and bone destruction due to simultaneous inhibition of both tumor growth and bone resorption

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Humoral bone morphogenetic protein 2 is sufficient for inducing breast cancer microcalcification.

30 September 2017

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Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass.

30 September 2017

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Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway

30 September 2017

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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

30 September 2017

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Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice

30 September 2017

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Regulation of muscle growth by multiple ligands signaling through activin type II receptors

30 September 2017

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Specificity and versatility in tgf-beta signaling through Smads

30 September 2017

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30 September 2017

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30 September 2017

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A novel transgenic chimaeric mouse system for the rapid functional evaluation of genes encoding secreted proteins

30 September 2017

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First evidence supporting a potential role for the BMP/SMAD pathway in the progression of oestrogen receptor-positive breast cancer.

30 September 2017

1 reference

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Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

30 September 2017

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Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts

30 September 2017

1 reference

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The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations

30 September 2017

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Identification of the haematopoietic stem cell niche and control of the niche size

30 September 2017

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Consequences of knocking out BMP signaling in the mouse

30 September 2017

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Genetic analysis of the mammalian transforming growth factor-beta superfamily

30 September 2017

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Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

30 September 2017

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Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

TGF-beta signal transduction

30 September 2017

1 reference

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Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of dalantercept, an activin receptor-like kinase-1 ligand trap, in patients with advanced cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

A comparison of mechanical properties derived from multiple skeletal sites in mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702141

21 September 2018

Identifiers

DOI

10.1038/SREP18849

1 reference

14 August 2017

1 reference

14 August 2017

1 reference