The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death. (Q36439720)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Stine Falsig Pedersen

series ordinal

1

1 reference

14 August 2017

4 April 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

452

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

249-259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16586098%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00424-006-0044-y

19 January 2020

exact match

0 references

cites work

Cell cycle-dependent expression of volume-activated chloride currents in nasopharyngeal carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Hyperosmotic stress activates Rho: differential involvement in Rho kinase-dependent MLC phosphorylation and NKCC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Osmotic stress activates Rac and Cdc42 in neutrophils: role in hypertonicity-induced actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Regulation of intracellular pH in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Amiloride delays the ischemia-induced rise in cytosolic free calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-006-0044-Y

Immunolocalization of NHE8 in rat kidney

21 January 2018

1 reference

12 December 2020

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

1 reference

12 December 2020

Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice

1 reference

12 December 2020

Shrinkage-induced Activation of the Na + /H + Exchanger in Ehrlich Ascites Tumor Cells: Mechanisms Involved in the Activation and a Role for the Exchanger in Cell Volume Regulation

1 reference

12 December 2020

Inhibition of Jurkat-T-lymphocyte Na+/H+-exchanger by CD95(Fas/Apo-1)-receptor stimulation

1 reference

12 December 2020

Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

1 reference

12 December 2020

A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide).

1 reference

12 December 2020

Cell cycle delay and apoptosis in response to osmotic stress.

1 reference

12 December 2020

Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway.

1 reference

12 December 2020

Chronic hypoxia elevates intracellular pH and activates Na+/H+ exchange in pulmonary arterial smooth muscle cells

1 reference

12 December 2020

ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells

1 reference

12 December 2020

The neighbor-joining method: a new method for reconstructing phylogenetic trees

1 reference

12 December 2020

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

1 reference

12 December 2020

Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition

1 reference

12 December 2020

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

1 reference

12 December 2020

Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase

1 reference

12 December 2020

Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium

1 reference

12 December 2020

Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts

1 reference

12 December 2020

Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes

1 reference

12 December 2020

Role of c-SRC and ERK in acid-induced activation of NHE3

1 reference

12 December 2020

Interdependent regulation of intracellular acidification and SHP-1 in apoptosis

1 reference

12 December 2020

Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells

1 reference

12 December 2020

MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals

1 reference

12 December 2020

Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation

1 reference

12 December 2020

The cytoskeleton and cell volume regulation

1 reference

12 December 2020

5-(N-Ethyl-N-isopropyl)-amiloride, an Na(+)-H(+) exchange inhibitor, protects gerbil hippocampal neurons from ischemic injury.

1 reference

12 December 2020

Mice with a null mutation in the NHE1 Na+-H+ exchanger are resistant to cardiac ischemia-reperfusion injury

1 reference

12 December 2020

Cell volume regulation: osmolytes, osmolyte transport, and signal transduction

1 reference

12 December 2020

GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channel

1 reference

12 December 2020

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

1 reference

12 December 2020

Ion channels and transporters on the move.

1 reference

12 December 2020

Na+-K+-2Cl- cotransport in Ehrlich cells: regulation by protein phosphatases and kinases.

1 reference

12 December 2020

Increases in [Ca2+]i and changes in intracellular pH during chemical anoxia in mouse neocortical neurons in primary culture.

1 reference

12 December 2020

ERM proteins and merlin: integrators at the cell cortex

1 reference

12 December 2020

Activation of Na(+)-H+ antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system

1 reference

12 December 2020

Role of intracellular pH in proliferation, transformation, and apoptosis

1 reference

12 December 2020

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

1 reference

12 December 2020

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

1 reference

12 December 2020

pH regulatory Na/H exchange by Amphiuma red blood cells

1 reference

12 December 2020

Cariporide (HOE642), a Selective Na + -H + Exchange Inhibitor, Inhibits the Mitochondrial Death Pathway

1 reference

12 December 2020

Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger

1 reference

12 December 2020

Is myosin light-chain phosphorylation a regulatory signal for the osmotic activation of the Na+-K+-2Cl- cotransporter?

1 reference

12 December 2020

Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.

1 reference

12 December 2020

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

1 reference

12 December 2020

Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins.

1 reference

12 December 2020

The Na(+)/H(+) exchanger SM-20220 attenuates ischemic injury in in vitro and in vivo models

1 reference

12 December 2020

Signal transduction mechanisms involved in the proliferation of C6 glioma cells induced by lysophosphatidic acid

1 reference

12 December 2020

Chloride channels go cell cycling

1 reference

12 December 2020

p21-activated protein kinase gamma-PAK is translocated and activated in response to hyperosmolarity. Implication of Cdc42 and phosphoinositide 3-kinase in a two-step mechanism for gamma-PAK activation

1 reference

12 December 2020

ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis

1 reference

12 December 2020

Shrinkage-induced activation of Na+/H+ exchange in primary rat astrocytes: role of myosin light-chain kinase

1 reference

12 December 2020

Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases

1 reference

12 December 2020

14‐3‐3γ Is upregulated by in vitro ischemia and binds to protein kinase Raf in primary cultures of astrocytes

1 reference

12 December 2020

Hypertonic saline impedes tumor cell-endothelial cell interaction by reducing adhesion molecule and laminin expression

1 reference

12 December 2020

Osmotic stress signaling and osmoadaptation in yeasts

1 reference

12 December 2020

14-3-3 proteins interact with specific MEK kinases

1 reference

12 December 2020

Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells

1 reference

12 December 2020

Physiological significance of volume-regulatory transporters.

1 reference

12 December 2020

Protein phosphatase regulation of Na+/H+ exchanger isoform I.

1 reference

12 December 2020

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

12 December 2020

Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.

1 reference

12 December 2020

Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy

1 reference

12 December 2020

Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation

1 reference

12 December 2020

The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites

1 reference

12 December 2020

Four deaths and a funeral: from caspases to alternative mechanisms.

1 reference

12 December 2020

Osmotically relevant membrane signaling complex: association between HB-EGF, beta(1)-integrin, and CD9 in mTAL

1 reference

12 December 2020

Sensors and Signal Transduction in the Activation of Cell Volume Regulatory Ion Transport Systems

1 reference

12 December 2020

Candidate inhibitor of the volume-sensitive kinase regulating K-Cl cotransport: the myosin light chain kinase inhibitor ML-7

1 reference

12 December 2020

p160ROCK mediates RhoA activation of Na-H exchange

1 reference

12 December 2020

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1 reference

12 December 2020

Functional significance of cell volume regulatory mechanisms.

1 reference

12 December 2020

Rho GTPases and their effector proteins

1 reference

12 December 2020

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines

1 reference

12 December 2020

Function and spatial distribution of ion channels and transporters in cell migration

1 reference

12 December 2020

Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells

1 reference

12 December 2020

Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death

1 reference

12 December 2020

Cytoplasmic acidification and activation of Na+/H+ exchange during regulatory volume decrease in Ehrlich ascites tumor cells

1 reference

12 December 2020

14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

1 reference

12 December 2020

Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes

1 reference

12 December 2020

Osmotic stimulation of the Na+/H+ exchanger NHE1: relationship to the activation of three MAPK pathways

1 reference

12 December 2020

Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells

1 reference

12 December 2020

Involvement of Na+/H+ exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis

1 reference

12 December 2020

pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells.

1 reference

12 December 2020

Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses

1 reference

12 December 2020

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

1 reference

12 December 2020

Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin.

1 reference

12 December 2020

Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels

1 reference

12 December 2020

Teleost Fh14-3-3a protein protects Xenopus oocytes from hyperosmolality

1 reference

12 December 2020

The relation between cellular sodium, pH and volumes and the activity of Na/H antiport during hypothermic ischemia: multinuclear NMR studies of rat hearts

1 reference

12 December 2020

Molecular physiology of vertebrate Na+/H+ exchangers

1 reference

12 December 2020

Effects of the Na+/H+ exchange inhibitor cariporide (HOE 642) on cardiac function and cardiomyocyte cell death in rat ischaemic-reperfused heart

1 reference

12 December 2020

Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress

1 reference

12 December 2020

Enhanced H+/ATP coupling ratio of H+-ATPase and increased 14-3-3 protein content in plasma membrane of tomato cells upon osmotic shock

1 reference

12 December 2020

Oxygen and carbon dioxide transport in vertebrate erythrocytes: an evolutionary change in the role of membrane transport

1 reference

12 December 2020

The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor

1 reference

12 December 2020

p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

1 reference

12 December 2020

Apoptosis, cell volume regulation and volume-regulatory chloride channels

1 reference

12 December 2020

A possible unifying principle for mechanosensation

1 reference

12 December 2020

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

1 reference

12 December 2020

Amiloride and analogues inhibit Na(+)-H+ exchange and cell proliferation in AR42J pancreatic cell line

1 reference

12 December 2020

Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

1 reference

12 December 2020

Regulation of Na+/H+ exchanger gene expression: mitogenic stimulation increases NHE1 promoter activity.

1 reference

12 December 2020

Oxygen-sensitive membrane transporters in vertebrate red cells.

1 reference

12 December 2020

Volume-sensitive myosin phosphorylation in vascular endothelial cells: correlation with Na-K-2Cl cotransport

1 reference

12 December 2020

14-3-3 proteins: key regulators of cell division, signalling and apoptosis.

1 reference

12 December 2020

Effects of hypertonic saline on expression of human polymorphonuclear leukocyte adhesion molecules.

1 reference

12 December 2020

Escaping cell death: survival proteins in cancer

1 reference

12 December 2020

Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes

1 reference

12 December 2020

Evolutionary origins of eukaryotic sodium/proton exchangers

1 reference

12 December 2020

Amiloride potentiates TRAIL-induced tumor cell apoptosis by intracellular acidification-dependent Akt inactivation.

1 reference

12 December 2020

Comparative biology of the ubiquitous Na+/H+ exchanger, NHE1: lessons from erythrocytes.

1 reference

12 December 2020

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

1 reference

12 December 2020

Cell size-dependent and independent proliferation of rodent neuroblastoma x glioma cells

1 reference

12 December 2020

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

1 reference

12 December 2020

The Ste20 group kinases as regulators of MAP kinase cascades

1 reference

12 December 2020