Hammerhead ribozymes: importance of stem-loop II for activity (Q36444559)

14 August 2017

Hammerhead ribozymes: importance of stem-loop II for activity (English)

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14 August 2017

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1

Tuschl T

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14 August 2017

Eckstein F

2

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PMCID

47061

14 August 2017

language of work or name

English

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publication date

1 August 1993

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

90

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14 August 2017

15

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14 August 2017

6991-6994

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Improved predictions of secondary structures for RNA

14 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

30 September 2017

RNA structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Improved free-energy parameters for predictions of RNA duplex stability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Sequence-dependent structural variations of hammerhead RNA enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

A thermodynamic study of unusually stable RNA and DNA hairpins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Structural Features that Give Rise to the Unusual Stability of RNA Hairpins Containing GNRA Loops

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Synthesis and NMR study of ribo-oligonucleotides forming a hammerhead-type RNA enzyme system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Studies on the structure and stabilizing factor of the CUUCGG hairpin RNA using chemically synthesized oligonucleotides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Substrate sequence effects on "hammerhead" RNA catalytic efficiency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Minimal sequence requirements for ribozyme activity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Numbering system for the hammerhead

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Importance of specific purine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Structure of an unusually stable RNA hairpin

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Sequence requirements of the hammerhead RNA self-cleavage reaction

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Characterization of the secondary structure and melting of a self-cleaved RNA hammerhead domain by proton NMR spectroscopy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Solution structure of an unusually stable RNA hairpin, 5GGAC(UUCG)GUCC

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Nuclease resistant ribozymes with high catalytic activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=47061

Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain

28 June 2018

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12 December 2020

Importance of specific adenosine N7-nitrogens for efficient cleavage by a hammerhead ribozyme. A model for magnesium binding

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12 December 2020

Kinetics of intermolecular cleavage by hammerhead ribozymes

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12 December 2020

Effects of GA mismatches on the structure and thermodynamics of RNA internal loops

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12 December 2020

Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence

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12 December 2020

Relationship between 2'-hydroxyls and magnesium binding in the hammerhead RNA domain: a model for ribozyme catalysis

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12 December 2020

Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

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12 December 2020

Study of a hammerhead ribozyme containing 2'-modified adenosine residues

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12 December 2020

The role of the exocyclic amino groups of conserved purines in hammerhead ribozyme cleavage

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12 December 2020

Identifiers

DOI

10.1073/PNAS.90.15.6991

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14 August 2017

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14 August 2017

1 reference

PMCID

47061