Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress (Q36444952)

14 August 2017

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title

Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress (English)

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14 August 2017

Helmut K Seitz

1

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PubMed ID

16606331

14 August 2017

Felix Stickel

series ordinal

2

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PubMed ID

16606331

14 August 2017

language of work or name

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1 April 2006

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14 August 2017

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14 August 2017

387

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14 August 2017

4

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14 August 2017

349-360

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Oxidants and antioxidants in alcohol-induced liver disease

14 August 2017

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Contribution of mitochondria to oxidative stress associated with alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The effect of ethanol-induced cytochrome p4502E1 on the inhibition of proteasome activity by alcohol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Neutrophilic infiltration in alcoholic hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. A prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Specific association between alcohol intake, high grade of differentiation and 4q34-q35 deletions in hepatocellular carcinomas identified by high resolution allelotyping

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Epidemiology of primary liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Primary liver cancer: worldwide incidence and trends

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Oxidative stress, toxicology, and pharmacology of CYP2E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alterations in DNA methylation may play a variety of roles in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

High rates of hepatocellular carcinoma in cirrhotic patients with high liver cell proliferative activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Hepatocellular carcinoma: recent trends in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Risk factors for the rising rates of primary liver cancer in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O6-methylguanine transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Hepatocellular carcinoma in cirrhosis: incidence and risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Hepatic mitochondrial glutathione: transport and role in disease and toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Calcineurin is required for translational control of protein synthesis in rat pancreatic acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol and mitochondria: a dysfunctional relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Should we change our dietary advice on cancer prevention?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Iron, hemochromatosis, and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Vitamin B6 deficiency in chronic liver disease--evidence for increased degradation of pyridoxal-5'-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Pathogenesis of hepatitis C-associated hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Vitamin B6 metabolism in chronic alcohol abuse. Pyridoxal phosphate levels in plasma and the effects of acetaldehyde on pyridoxal phosphate synthesis and degradation in human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

21 January 2018

Alcohol and liver cancer

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Inhibitory effects of beta-carotene and vitamin a during the progression phase of hepatocarcinogenesis involve inhibition of cell proliferation but not alterations in DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol and hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol, iron-associated oxidative stress, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Hepatic iron overload in alcoholic liver disease: why does it occur and what is its role in pathogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol and retinoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Enhancement of ethanol induced rectal mucosal hyper regeneration with age in F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Cocarcinogenic effects of alcohol in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Case-control study on hepatitis C virus (HCV) as a risk factor for hepatocellular carcinoma: the role of HCV genotypes and the synergism with hepatitis B virus and alcohol. Brescia HCC Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Association between high serum alanine aminotransferase levels and more rapid development and higher rate of incidence of hepatocellular carcinoma in patients with hepatitis C virus-associated cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Endotoxin, endotoxin-neutralizing-capacity, sCD14, sICAM-1, and cytokines in patients with various degrees of alcoholic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Tumor necrosis factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1 (c-Jun and c-Fos) expression in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Alcohol, vitamin A, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Environmental factors and risk for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Effective Utilization ofN2-Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases†

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

Nucleolar hypertrophy correlates with hepatocellular carcinoma development in cirrhosis due to HBV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.047

21 January 2018

Identifiers

DOI

10.1515/BC.2006.047

1 reference

14 August 2017

1 reference

PubMed ID

16606331