Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors (Q36454792)

14 August 2017

Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors (English)

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14 August 2017

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Lars H Lindner

2

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author name string

Ashley A Manzoor

1

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14 August 2017

Chelsea D Landon

3

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14 August 2017

Ji-Young Park

4

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14 August 2017

Andrew J Simnick

5

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14 August 2017

Matthew R Dreher

6

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14 August 2017

Shiva Das

7

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14 August 2017

Gabi Hanna

8

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14 August 2017

Won Park

9

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14 August 2017

Ashutosh Chilkoti

10

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14 August 2017

Gerben A Koning

11

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14 August 2017

Timo L M ten Hagen

12

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14 August 2017

David Needham

13

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14 August 2017

Mark W Dewhirst

14

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14 August 2017

language of work or name

English

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publication date

4 September 2012

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14 August 2017

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14 August 2017

72

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14 August 2017

21

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14 August 2017

5566-5575

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Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Effect of pazopanib on tumor microenvironment and liposome delivery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Lyso-thermosensitive liposomal doxorubicin: a novel approach to enhance efficacy of thermal ablation of liver cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

The Kadota Fund International Forum 2004--clinical group consensus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Tumor necrosis factor alpha mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Drug penetration in solid tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

A mathematical model for comparison of bolus injection, continuous infusion, and liposomal delivery of doxorubicin to tumor cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Doxorubicin gradients in human breast cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Liposomal drug formulations. Rationale for development and what we can expect for the future

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Hyperthermic treatment of malignant diseases: current status and a view toward the future.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Design of Liposomes for Enhanced Local Release of Drugs by Hyperthermia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Thermochemotherapy in patients with extremity high-risk soft tissue sarcomas (HR-STS).

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Effects of fluctuating oxygenation on tirapazamine efficacy: Theoretical predictions.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Novel temperature-sensitive liposomes with prolonged circulation time

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Tumor vascularity: a histological measure of angiogenesis and hypoxia.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517817

Selective delivery of liposome-associated cis-dichlorodiammineplatinum(II) by heat and its influence on tumor drug uptake and growth

21 September 2018

1 reference

12 December 2020

Treatment of solid L1210 murine tumors with local hyperthermia and temperature-sensitive liposomes containing methotrexate

1 reference

12 December 2020

Direct visualization of heterogeneous extravascular distribution of trastuzumab in human epidermal growth factor receptor type 2 overexpressing xenografts

1 reference

12 December 2020

Polymersomes: Tough Vesicles Made from Diblock Copolymers

1 reference

12 December 2020

Doxorubicin pharmacokinetics after intravenous and intraperitoneal administration in the nude mouse

1 reference

12 December 2020

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft

1 reference

12 December 2020

A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model

1 reference

12 December 2020

A transparent access chamber for the rat dorsal skin fold

1 reference

12 December 2020

Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature

1 reference

12 December 2020

In vitro stability and content release properties of phosphatidylglyceroglycerol containing thermosensitive liposomes

1 reference

12 December 2020

Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs

1 reference

12 December 2020

10.1158/0008-5472.CAN-12-1683

Identifiers

DOI

1 reference

14 August 2017

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14 August 2017

PubMed publication ID

22952218

1 reference