Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis (Q36459133)

14 August 2017

Complement 5a receptor-mediated neutrophil dysfunction is associated with a poor outcome in sepsis (English)

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14 August 2017

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Ruonan Xu

1

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14 August 2017

Fang Lin

2

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14 August 2017

Chunmei Bao

3

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14 August 2017

Huihuang Huang

4

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14 August 2017

Chengcheng Ji

5

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14 August 2017

Siyu Wang

6

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14 August 2017

Lei Jin

7

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14 August 2017

Lijian Sun

8

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14 August 2017

Ke Li

9

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14 August 2017

Zheng Zhang

10

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14 August 2017

Fu-Sheng Wang

11

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14 August 2017

2 March 2015

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Cellular and Molecular Immunology

14 August 2017

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14 August 2017

13

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14 August 2017

1

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14 August 2017

103-109

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Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

C5L2: a controversial receptor of complement anaphylatoxin, C5a

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

C5a mediates peripheral blood neutrophil dysfunction in critically ill patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

A key role of C5a/C5aR activation for the development of sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

C5L2, a nonsignaling C5A binding protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Complement-induced impairment of innate immunity during sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Epidemiology of sepsis: an update

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Severe sepsis and septic shock. Definitions, epidemiology, and clinical manifestations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Changes and regulation of the C5a receptor on neutrophils during septic shock in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

High C5a levels are associated with increased mortality in sepsis patients--no enhancing effect by actin-free Gc-globulin

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Neutrophil C5a receptor and the outcome in a rat model of sepsis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Altered neutrophil trafficking during sepsis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711680

Neutrophil dysfunction in sepsis. II. Evidence for the role of complement activation products in cellular deactivation

21 September 2018

1 reference

12 December 2020

Monocyte deactivation in septic patients: restoration by IFN-gamma treatment

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12 December 2020

Patients with acute on chronic liver failure display "sepsis-like" immune paralysis

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12 December 2020

Neutrophils as potential therapeutic targets in sepsis

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12 December 2020

Identifiers

DOI

10.1038/CMI.2014.136

1 reference

14 August 2017

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14 August 2017

PubMed publication ID

25726869

1 reference