New directions in kinetic high information content assays (Q36460541)

14 August 2017

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title

New directions in kinetic high information content assays (English)

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14 August 2017

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Peter B Simpson

1

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14 August 2017

Keith A Wafford

series ordinal

2

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14 August 2017

publication date

1 March 2006

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14 August 2017

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14 August 2017

volume

11

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14 August 2017

issue

5-6

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14 August 2017

page(s)

237-244

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Real-time molecular and cellular analysis: the new frontier of drug discovery

14 August 2017

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Techniques: high-throughput measurement of intracellular Ca(2+) -- back to basics.

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Retinoic acid evoked-differentiation of neuroblastoma cells predominates over growth factor stimulation: an automated image capture and quantitation approach to neuritogenesis

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Fluorescence readouts in HTS: no gain without pain?

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7 January 2021

Quantitative assays of chemotaxis and chemokinesis for human neural cells

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Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system.

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Oscillations in NF-kappaB signaling control the dynamics of gene expression

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Sensitivity analysis of parameters controlling oscillatory signalling in the NF-kappaB pathway: the roles of IKK and IkappaBalpha

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

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Comment on "Oscillations in NF-kappaB signaling control the dynamics of gene expression".

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Dynamics of the p53-Mdm2 feedback loop in individual cells

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Nuclear export inhibitors and kinase inhibitors identified using a MAPK-activated protein kinase 2 redistribution screen

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Translocation biosensors to study signal-specific nucleo-cytoplasmic transport, protease activity and protein-protein interactions

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Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer

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Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

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Ionworks HT: a new high-throughput electrophysiology measurement platform.

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Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity

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Substance identification by quantitative characterization of oscillatory activity in murine spinal cord networks on microelectrode arrays

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Learning in networks of cortical neurons.

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Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays

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Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader

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7 January 2021

Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides

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7 January 2021

High content screening applied to large-scale cell biology

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7 January 2021

Highly sensitive fluorescence detection technology currently available for HTS.

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7 January 2021

Fluorescence lifetime imaging microscopy (flimscopy). Methodology development and application to studies of endosome fusion in single cells

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7 January 2021

Imaging fluorescence lifetime heterogeneity applied to GFP-tagged MHC protein at an immunological synapse.

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7 January 2021

Fast fluorescence lifetime imaging of calcium in living cells

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7 January 2021

High content kinetic assays of neuronal signaling implemented on BD pathway HT.

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7 January 2021

Determination of electrical properties of ES cell-derived cardiomyocytes using MEAs.

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QT-screen: high-throughput cardiac safety pharmacology by extracellular electrophysiology on primary cardiac myocytes

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Visualizing phosphoinositide signalling in single neurons gets a green light

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7 January 2021

Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.

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7 January 2021

Intracellular signalling. Receptor-specific messenger oscillations

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7 January 2021

The Use of Biosensors to Study GPCR Function: Applications for High-Content Screening

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7 January 2021

High-content assays for ligand regulation of G-protein-coupled receptors

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7 January 2021

A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells

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7 January 2021

Specific covalent labeling of recombinant protein molecules inside live cells

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7 January 2021

Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling

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Painting protein misfolding in the cell in real time with an atomic-scale brush

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7 January 2021

Enzyme fragment complementation: a flexible high throughput screening assay technology

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7 January 2021

Homogeneous assays for cellular protein degradation using beta-galactosidase complementation: NF-kappaB/IkappaB pathway signaling

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7 January 2021

Measuring drug action in the cellular context using protein-fragment complementation assays

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7 January 2021

Extracellular recordings from patterned neuronal networks using planar microelectrode arrays

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7 January 2021

Neuronal Ca2+ stores: activation and function

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7 January 2021

NMDA receptor-dependent periodic oscillations in cultured spinal cord networks

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7 January 2021

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Identifiers

DOI

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14 August 2017

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