Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. (Q36468902)

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11 February 2020

title

Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype (English)

1 reference

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11 February 2020

0 references

5

1 reference

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11 February 2020

author name string

Baozhi Yuan

1

1 reference

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11 February 2020

Jian Q Feng

2

1 reference

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11 February 2020

Stephen Bowman

3

1 reference

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11 February 2020

Ying Liu

4

1 reference

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11 February 2020

Iris Lindberg

6

1 reference

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11 February 2020

Marc K Drezner

7

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11 February 2020

publication date

1 January 2013

1 reference

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Journal of Bone and Mineral Research

11 February 2020

published in

1 reference

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11 February 2020

volume

28

1 reference

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11 February 2020

issue

1

1 reference

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11 February 2020

page(s)

56-72

1 reference

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describes a project that uses

11 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3523095/fullTextXML

inferred from PubMed Central ID database lookup

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30 September 2017

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Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease

30 September 2017

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30 September 2017

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30 September 2017

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Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP).

30 September 2017

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Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice

30 September 2017

1 reference

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Human prohormone convertase 3 gene: exon-intron organization and molecular scanning for mutations in Japanese subjects with NIDDM.

30 September 2017

1 reference

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7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elements

30 September 2017

1 reference

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7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity

30 September 2017

1 reference

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7B2 is a specific intracellular binding protein of the prohormone convertase PC2

30 September 2017

1 reference

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A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

30 September 2017

1 reference

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Abnormal regulation of renal 25-hydroxyvitamin D-1 alpha-hydroxylase activity in the X-linked hypophosphatemic mouse

30 September 2017

1 reference

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Evaluation of a Role for 1,25-Dihydroxyvitamin D3 in the Pathogenesis and Treatment of X-linked Hypophosphatemic Rickets and Osteomalacia

30 September 2017

1 reference

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Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.

30 September 2017

1 reference

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Neuroendocrine protein 7B2 is essential for proteolytic conversion and activation of proprotein convertase 2 in vivo.

28 June 2018

1 reference

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cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone

28 June 2018

1 reference

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Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets/osteomalacia.

28 June 2018

1 reference

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Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.

21 September 2018

1 reference

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DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Pathogenic role of Fgf23 in Hyp mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

A novel homozygous missense mutation in FGF23 causes Familial Tumoral Calcinosis associated with disseminated visceral calcification

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Evidence for abnormal translational regulation of renal 25-hydroxyvitamin D-1alpha-hydroxylase activity in the hyp-mouse

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Dentin matrix protein 1 initiates hydroxyapatite formation in vitro

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Evidence for the proteolytic processing of dentin matrix protein 1. Identification and characterization of processed fragments and cleavage sites

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523095

Processing and sorting of the prohormone convertase 2 propeptide

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886699

12 December 2020

inferred from PubMed ID database lookup

The efficacy of vitamin D2 and oral phosphorus therapy in X-linked hypophosphatemic rickets and osteomalacia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886699

12 December 2020

inferred from PubMed ID database lookup

A novel recessive mutation in fibroblast growth factor-23 causes familial tumoral calcinosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22886699

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/JBMR.1738

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22886699%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22886699%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22886699%20AND%20SRC:MED&resulttype=core&format=json