Piperine, a dietary phytochemical, inhibits angiogenesis (Q36472386)

14 August 2017

Piperine, a dietary phytochemical, inhibits angiogenesis (English)

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14 August 2017

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Carolyn D Doucette

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14 August 2017

Ashley L Hilchie

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2

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14 August 2017

Robert Liwski

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3

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14 August 2017

David W Hoskin

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4

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14 August 2017

16 August 2012

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Journal of Nutritional Biochemistry

14 August 2017

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14 August 2017

24

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14 August 2017

1

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14 August 2017

231-239

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describes a project that uses

14 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3524266/fullTextXML

inferred from PubMed Central ID database lookup

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Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.

30 September 2017

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30 September 2017

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Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

30 September 2017

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Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.

30 September 2017

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1,4-Naphthoquinone is a potent inhibitor of human cancer cell growth and angiogenesis

30 September 2017

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Transient receptor potential vanilloid 1-mediated expression and secretion of endothelial cell-derived calcitonin gene-related peptide

30 September 2017

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30 September 2017

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Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers

30 September 2017

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30 September 2017

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30 September 2017

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Akt1 in endothelial cell and angiogenesis

30 September 2017

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Viral nanoparticles as tools for intravital vascular imaging

30 September 2017

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30 September 2017

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Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

30 September 2017

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Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells

30 September 2017

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

30 September 2017

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Angiogenesis in health and disease

30 September 2017

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Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.

30 September 2017

1 reference

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Role of Akt signaling in vascular homeostasis and angiogenesis

30 September 2017

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Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents

30 September 2017

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

30 September 2017

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

30 September 2017

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

30 September 2017

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Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease

30 September 2017

1 reference

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Immunomodulatory and antitumor activity of Piper longum Linn. and piperine

28 June 2018

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Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells

28 June 2018

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Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells

28 June 2018

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Inhibition of lipopolysaccharide-induced inflammatory responses by piperine

28 June 2018

1 reference

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Pharmacologic antagonism of the oral aversive taste-directed response to capsaicin in a mouse brief access taste aversion assay

21 September 2018

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Cisplatin reduces endothelial cell migration via regulation of type 2-matrix metalloproteinase activity

21 September 2018

1 reference

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Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model

21 September 2018

1 reference

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Effect of piperine on the inhibition of nitric oxide (NO) and TNF-alpha production

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Blood pressure lowering and vasomodulator effects of piperine

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Piperine: researchers discover new flavor in an ancient spice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Effect of piperine on the inhibition of lung metastasis induced B16F-10 melanoma cells in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524266

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 September 2018

1 reference

12 December 2020

Mapping of the Sites Involved in Ligand Association and Dissociation at the Extracellular Domain of the Kinase Insert Domain-containing Receptor for Vascular Endothelial Growth Factor

1 reference

12 December 2020

Piperine modulation of carcinogen induced oxidative stress in intestinal mucosa

1 reference

12 December 2020

Piperine inhibits TNF-alpha induced adhesion of neutrophils to endothelial monolayer through suppression of NF-kappaB and IkappaB kinase activation

1 reference

12 December 2020

Signal transduction by vascular endothelial growth factor receptors

1 reference

12 December 2020

10.1016/J.JNUTBIO.2012.05.009

Identifiers

DOI

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14 August 2017

1 reference

14 August 2017

PubMed publication ID

22902327

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