Next revolution in the molecular theranostics of infectious diseases: microfabricated systems for personalized medicine (Q36481129)

14 August 2017

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title

Next revolution in the molecular theranostics of infectious diseases: microfabricated systems for personalized medicine (English)

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14 August 2017

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personalized medicine

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Luc Bissonnette

1

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PubMed ID

16706745

14 August 2017

Michel G Bergeron

series ordinal

2

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14 August 2017

1 May 2006

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

14 August 2017

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14 August 2017

6

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14 August 2017

3

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14 August 2017

433-450

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Changing patterns of infectious disease

14 August 2017

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Examining unmet needs in infectious disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

The challenge of emerging and re-emerging infectious diseases

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Emerging infectious diseases: a clear and present danger to humanity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Rapid molecular theranostics in infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Toward rapid real-time molecular diagnostic to guide smart use of antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Confronting bacterial resistance in healthcare settings: a crucial role for microbiologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular detection and genotyping of pathogens: more accurate and rapid answers

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular genetic methods for the diagnosis of fastidious microorganisms

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Real-time PCR in the microbiology laboratory

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

New developments in the diagnosis of bloodstream infections

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

What does the future hold for clinical microbiology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

PCR-based diagnostics for infectious diseases: uses, limitations, and future applications in acute-care settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Nucleic acid-based methods for the detection of bacterial pathogens: present and future considerations for the clinical laboratory

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

False-positive results and contamination in nucleic acid amplification assays: suggestions for a prevent and destroy strategy

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular diagnostics: hurdles for clinical implementation.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

New real-time PCR assay for rapid detection of methicillin-resistant Staphylococcus aureus directly from specimens containing a mixture of staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Toward resolving the challenges of sepsis diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Mixed microbial aetiology of community-acquired pneumonia in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Sexually transmitted diseases (STDs)--a synoptic overview for urologists

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Sexually transmissible infections other than HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Chips with everything: DNA microarrays in infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Highly parallel microbial diagnostics using oligonucleotide microarrays.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

The future of home testing--implications for traditional laboratories

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Point-of-care molecular diagnostic systems--past, present and future

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Diagnostics for the developing world

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Top ten biotechnologies for improving health in developing countries

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacogenomics: unlocking the human genome for better drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Genetic testing for pharmacogenetics and its clinical application in drug therapy

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacogenetics goes genomic

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacogenetics of Drug Metabolising Enzymes: Importance for Personalised Medicine

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Moving towards individualized medicine with pharmacogenomics

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Cytochromes P450 and metabolism of xenobiotics

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Interactions between herbal medicines and prescribed drugs: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Drug interactions with herbal products and grapefruit juice: a conference report

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Natural health products and drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

The role of metabolic activation in drug-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Genetics and genomics in infectious disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Balanced polymorphism selected by genetic versus infectious human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

SLC11A1 (formerly NRAMP1) and disease resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacogenomics: translating functional genomics into rational therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Pharmacogenetics: potential for individualized drug therapy through genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Miniaturization and integration: challenges and breakthroughs in microfluidics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic chips for clinical and forensic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Introduction to micro-analytical systems: bioanalytical and pharmaceutical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic approaches to malaria detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Micro total analysis system (micro-TAS) in biotechnology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Micro total analysis systems. Recent developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Thermally-actuated, phase change flow control for microfluidic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Miniaturized detection technology in molecular diagnostics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Immunomagnetic T cell capture from blood for PCR analysis using microfluidic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Dealing with real samples: sample pre-treatment in microfluidic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Using biofunctional magnetic nanoparticles to capture vancomycin-resistant enterococci and other gram-positive bacteria at ultralow concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Separation of biomolecules using electrophoresis and nanostructures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Laser induced disruption of bacterial spores on a microchip.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Cell lysis on a microfluidic CD (compact disc).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microchip-based purification of DNA from biological samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic chip for high efficiency DNA extraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Solid supports for micro analytical systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Controlled microfluidic interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Single-molecule reader for proteomics and genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Thermosiphon-based PCR reactor: experiment and modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Rapid PCR in a continuous flow device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Bulk-micromachined submicroliter-volume PCR chip with very rapid thermal response and low power consumption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfabricated PCR-electrochemical device for simultaneous DNA amplification and detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular diagnostics on electrophoretic microchips

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

DNA diagnosis by capillary electrophoresis and microfabricated electrophoretic devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Integrated portable genetic analysis microsystem for pathogen/infectious disease detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfabricated systems for nucleic acid analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Ligase detection reaction/hybridization assays using three-dimensional microfluidic networks for the detection of low-abundant DNA point mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Real-time nucleic acid sequence-based amplification in nanoliter volumes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Helicase-dependent isothermal DNA amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Using DNA microarrays for diagnostic and prognostic prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Medical applications of microarray technologies: a regulatory science perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Challenges and opportunities for pathogen detection using DNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Micro total analysis systems. 1. Introduction, theory, and technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Rapid fabrication of a poly(dimethylsiloxane) microfluidic capillary gel electrophoresis system utilizing high precision machining

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Polymer microfluidic chip for online monitoring of microarray hybridizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Electrokinetically based approach for single-nucleotide polymorphism discrimination using a microfluidic device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic device for rapid (<15 min) automated microarray hybridization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Plastic biochannel hybridization devices: a new concept for microfluidic DNA arrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic chip for fast nucleic acid hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microelectronic array devices and techniques for electric field enhanced DNA hybridization in low-conductance buffers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Electronic microarray analysis of 16S rDNA amplicons for bacterial detection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Quantitative, multiplexed detection of bacterial pathogens: DNA and protein applications of the Luminex LabMAP system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Use of the DNA flow-thru chip, a three-dimensional biochip, for typing and subtyping of influenza viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Advanced sequencing technologies: methods and goals

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfabricated electrophoresis systems for DNA sequencing and genotyping applications: current technology and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Micro- and nanofluidics for DNA analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

New biochip technology for label-free detection of pathogens and their toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

DNA detection by integrable electronics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Labelfree fully electronic nucleic acid detection system based on a field-effect transistor device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Structured thin films as functional components within biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Multi-analyte surface plasmon resonance biosensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Optical sensors based on hybrid aptamer/conjugated polymer complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Methods for strand-specific DNA detection with cationic conjugated polymers suitable for incorporation into DNA chips and microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Detection of target DNA using fluorescent cationic polymer and peptide nucleic acid probes on solid support

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Direct molecular detection of nucleic acids by fluorescence signal amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microcantilever biosensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Dynamic microcantilever sensors for discerning biomolecular interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Nanotechnology in clinical laboratory diagnostics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Microfluidic immunosensor systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

A portable array biosensor for detecting multiple analytes in complex samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Protein microarray detection strategies: focus on direct detection technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Technology and applications of protein microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Advances in functional protein microarray technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Aptasensors--the future of biosensing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Analytical applications of aptamers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Point-of-care immunotesting: approaching the analytical performance of central laboratory methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Adapting arrays and lab-on-a-chip technology for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Design of a compact disk-like microfluidic platform for enzyme-linked immunosorbent assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Development of a novel microfluidic immunoassay for the detection of Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Evanescent wave fluorescence biosensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Photoaptamer arrays applied to multiplexed proteomic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Aptamers--basic research, drug development, and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Label-free electrochemical detection for aptamer-based array electrodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Aptamer-derived nucleic acid oligos: applications to develop nucleic acid chips to analyze proteins and small ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Catching bacteria with sugar

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Tools for glycomics: mapping interactions of carbohydrates in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Protein and Chemical Microarrays—Powerful Tools for Proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Immobilized probe and glass surface chemistry as variables in microarray fabrication

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Fabrication of high quality microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular approaches to diagnosing and managing infectious diseases: practicality and costs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

How to avoid another 'Vioxx'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Disposable microfluidic devices: fabrication, function, and application

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Label-Free Detection of DNA Hybridization at the Nanoscale: A Highly Sensitive and Selective Approach Using Atomic-Force Microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

The Use of Nanoarrays for Highly Sensitive and Selective Detection of Human Immunodeficiency Virus Type 1 in Plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Lysozyme for capture of microorganisms on protein biochips

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Molecular diagnostics: an FDA perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Rapid detection of group B streptococci in pregnant women at delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

PCR in a Rayleigh-Benard Convection Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Hybridization enhancement using cavitation microstreaming

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Fluorescent polymeric transducer for the rapid, simple, and specific detection of nucleic acids at the zeptomole level

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

Detection limits for nanoscale biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.433

21 January 2018

Identifiers

DOI

10.1586/14737159.6.3.433

1 reference

14 August 2017

1 reference

PubMed ID

16706745