Cisplatin-Induced Downregulation of OCTN2 Affects Carnitine Wasting (Q36491674)

14 August 2017

Cisplatin-induced downregulation of OCTN2 affects carnitine wasting (English)

1 reference

14 August 2017

Cisplatin-Induced Downregulation of OCTN2 Affects Carnitine Wasting (English)

1 reference

10.1158/1078-0432.CCR-10-1239

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DOI

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-1239

17 July 2024

9

Alex Sparreboom

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14 August 2017

Chaoxin Hu

2

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14 August 2017

Zhaoyuan Chen

6

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14 August 2017

Zhili Zuo

7

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14 August 2017

Cynthia S. Lancaster

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

17 July 2024

Ryan M. Franke

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17 July 2024

Kelly K. Filipski

4

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17 July 2024

Shelley J. Orwick

5

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17 July 2024

Walter J. Loos

8

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17 July 2024

language of work or name

English

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publication date

21 September 2010

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full work available at URL

14 August 2017

https://aacrjournals.org/clincancerres/article-pdf/16/19/4789/1991656/4789.pdf

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

http://clincancerres.aacrjournals.org/cgi/content/abstract/16/19/4789

17 July 2024

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20858838/?tool=EBI

17 July 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20858838/pdf/?tool=EBI

17 July 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

https://europepmc.org/articles/PMC3531239

17 July 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

https://europepmc.org/articles/PMC3531239?pdf=render

17 July 2024

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

https://doi.org/10.1158/1078-0432.ccr-10-1239

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858838

https://aacrjournals.org/clincancerres/article-pdf/16/19/4789/1991656/4789.pdf

17 July 2024

1 reference

10.1158/1078-0432.CCR-10-1239

Crossref

DOI

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-1239

17 July 2024

published in

Clinical Cancer Research

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14 August 2017

16

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14 August 2017

19

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14 August 2017

4789-4799

1 reference

Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase

14 August 2017

1 reference

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30 September 2017

1 reference

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Mouse OCTN2 is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha) via a PPRE located in the first intron

30 September 2017

1 reference

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Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity

30 September 2017

1 reference

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Novel inhibitors of human organic cation/carnitine transporter (hOCTN2) via computational modeling and in vitro testing

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1 reference

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1 reference

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1 reference

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30 September 2017

1 reference

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Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation.

30 September 2017

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Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells

30 September 2017

1 reference

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30 September 2017

1 reference

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The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

Disorders of carnitine transport and the carnitine cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.

30 September 2017

1 reference

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Functional regions of organic cation/carnitine transporter OCTN2 (SLC22A5): roles in carnitine recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

Carnitine: transport and physiological functions in the brain.

30 September 2017

1 reference

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

30 September 2017

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3D-Jury: a simple approach to improve protein structure predictions

30 September 2017

1 reference

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Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function

30 September 2017

1 reference

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Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter

30 September 2017

1 reference

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30 September 2017

1 reference

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

30 September 2017

1 reference

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30 September 2017

1 reference

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30 September 2017

1 reference

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Reversal of cisplatin-induced carnitine deficiency and energy starvation by propionyl-L-carnitine in rat kidney tissues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

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28 June 2018

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Evaluation of the effect of acetyl L-carnitine on experimental cisplatin nephrotoxicity.

28 June 2018

1 reference

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Urinary excretion of carnitine as a marker of proximal tubular damage associated with platin-based antineoplastic drugs

21 September 2018

1 reference

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Carnitine plasma levels and fatigue in children/adolescents receiving cisplatin, ifosfamide, or doxorubicin

21 September 2018

1 reference

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Carnitine/organic cation transporter OCTN2 (Slc22a5) is responsible for renal secretion of cephaloridine in mice

21 September 2018

1 reference

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Cisplatin-induced kidney injury in the rat: L-carnitine modulates the relationship between MMP-9 and TIMP-3.

21 September 2018

1 reference

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Interaction of Cisplatin with the human organic cation transporter 2.

21 September 2018

1 reference

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21 September 2018

1 reference

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Alterations of PPARalpha and its coactivator PGC-1 in cisplatin-induced acute renal failure

21 September 2018

1 reference

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L-Carnitine inhibits cisplatin-induced injury of the kidney and small intestine

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531239

A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse

21 September 2018

1 reference

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Defective urinary carnitine transport in heterozygotes for primary carnitine deficiency

21 September 2018

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12 December 2020

Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis

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12 December 2020

Renal handling of free and acylcarnitine in secondary carnitine deficiency

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12 December 2020

Valproate treatment and carnitine deficiency

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12 December 2020

Infantile disease with microvesicular fatty infiltration of viscera spontaneously occurring in the C3H-H-2° strain of mouse with similarities to Reye's syndrome

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12 December 2020

Influence of glutathione administration on the disposition of free and total platinum in patients after administration of cisplatin

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12 December 2020

Augmentation of transport for cisplatin-glutathione adduct in cisplatin-resistant cancer cells

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12 December 2020

Increased urinary excretion of carnitine in patients treated with cisplatin

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12 December 2020

Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)

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12 December 2020

Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment

1 reference

12 December 2020

10.1158/1078-0432.CCR-10-1239

Identifiers

DOI

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14 August 2017

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14 August 2017

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