A kinesin switch I arginine to lysine mutation rescues microtubule function (Q36492504)

14 August 2017

A kinesin switch I arginine to lysine mutation rescues microtubule function (English)

1 reference

14 August 2017

Lisa M Klumpp

1

1 reference

14 August 2017

Andrew T Mackey

2

1 reference

14 August 2017

Christopher M Farrell

3

1 reference

14 August 2017

John M Rosenberg

4

1 reference

14 August 2017

Susan P Gilbert

5

1 reference

14 August 2017

language of work or name

English

0 references

publication date

14 July 2003

1 reference

Journal of Biological Chemistry

14 August 2017

1 reference

14 August 2017

278

1 reference

14 August 2017

40

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14 August 2017

39059-39067

1 reference

EPR Spectroscopy Shows a Microtubule-Dependent Conformational Change in the Kinesin Switch 1 Domain

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Nucleotide-induced conformations in the neck region of dimeric kinesin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Early stages of energy transduction by myosin: roles of Arg in switch I, of Glu in switch II, and of the salt-bridge between them

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Kinesin: switch I & II and the motor mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

A structural pathway for activation of the kinesin motor ATPase.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Switch-based mechanism of kinesin motors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Structure of a genetically engineered molecular motor.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Molecular dynamics study of the energetic, mechanistic, and structural implications of a closed phosphate tube in ncd

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Kinetics: a tool to study molecular motors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing conformational change

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Structural mechanism of muscle contraction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

The way things move: looking under the hood of molecular motor proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

A structural change in the kinesin motor protein that drives motility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Lethal kinesin mutations reveal amino acids important for ATPase activation and structural coupling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Motor proteins of the kinesin family. Structures, variations, and nucleotide binding sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

The case for a common ancestor: kinesin and myosin motor proteins and G proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Direction determination in the minus-end-directed kinesin motor ncd

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Functional transitions in myosin: formation of a critical salt-bridge and transmission of effect to the sensitive tryptophan.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

The crystal structure of dimeric kinesin and implications for microtubule-dependent motility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

X-ray structure of motor and neck domains from rat brain kinesin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Opening of the myosin nucleotide triphosphate binding domain during the ATPase cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Reversal in the direction of movement of a molecular motor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Switches, latches, and amplifiers: common themes of G proteins and molecular motors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Active site comparisons highlight structural similarities between myosin and other P-loop proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Crystal structure of the kinesin motor domain reveals a structural similarity to myosin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Pathway of processive ATP hydrolysis by kinesin.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Kinesin ATPase: rate-limiting ADP release

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Bovine brain kinesin is a microtubule-activated ATPase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Improved methods for building protein models in electron density maps and the location of errors in these models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Role of the kinesin neck linker and catalytic core in microtubule-based motility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Coupled chemical and mechanical reaction steps in a processive Neurospora kinesin

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Pre-steady-state kinetics of the microtubule-kinesin ATPase.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265777

Swing of the lever arm of a myosin motor at the isomerization and phosphate-release steps.

28 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

The structure of the nucleotide-binding site of kinesin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Mutational analysis of the switch II loop of Dictyostelium myosin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

The role of ATP hydrolysis for kinesin processivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Determinants of kinesin motor polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

ATP reorients the neck linker of kinesin in two sequential steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Alternating site mechanism of the kinesin ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Expression, purification, and characterization of the Drosophila kinesin motor domain produced in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Sedimentation studies on the kinesin motor domain constructs K401, K366, and K341.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Motor domain mutation traps kinesin as a microtubule rigor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Measuring kinesin's first step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Force production by single kinesin motors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

A mechanistic model for Ncd directionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Pathway of ADP-stimulated ADP release and dissociation of tethered kinesin from microtubules. Implications for the extent of processivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Alanine scanning mutagenesis of the switch I region in the ATPase site of Dictyostelium discoideum myosin II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Pathway of ATP hydrolysis by monomeric and dimeric kinesin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Interacting head mechanism of microtubule-kinesin ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Equilibrium binding studies of non-claret disjunctional protein (Ncd) reveal cooperative interactions between the motor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Moving a microtubule may require two heads: a kinetic investigation of monomeric Ncd

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

Mechanism of microtubule kinesin ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

The structural and mechanochemical cycle of kinesin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304250200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304250200

1 reference

14 August 2017

1 reference

14 August 2017

1 reference