Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection (Q36498200)

14 August 2017

Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection (English)

1 reference

14 August 2017

4

Samuel H Speck

1 reference

14 August 2017

Jeremy H Herskowitz

1

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14 August 2017

Andrea M Siegel

series ordinal

2

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14 August 2017

Meagan A Jacoby

series ordinal

3

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14 August 2017

language of work or name

English

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publication date

30 January 2008

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14 August 2017

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14 August 2017

82

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14 August 2017

7

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14 August 2017

3295-3310

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describes a project that uses

14 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2268483/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Murine gamma-herpesvirus 68 latency protein M2 binds to Vav signaling proteins and inhibits B-cell receptor-induced cell cycle arrest and apoptosis in WEHI-231 B cells.

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Role of B-cell proliferation in the establishment of gammaherpesvirus latency

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COX-2 Induction during Murine Gammaherpesvirus 68 Infection Leads to Enhancement of Viral Gene Expression

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Transcription program of murine gammaherpesvirus 68

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Murid herpesvirus 4 strain 68 M2 protein is a B-cell-associated antigen important for latency but not lymphocytosis

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Long-term latent murine Gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo

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Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency

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The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

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Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

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Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation

30 September 2017

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Control of Epstein-Barr virus reactivation by activated CD40 and viral latent membrane protein 1.

30 September 2017

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Dissecting the host response to a gamma-herpesvirus

30 September 2017

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Natural history of murine -herpesvirus infection

30 September 2017

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The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell

30 September 2017

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Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome

30 September 2017

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WW- and SH3-domain interactions with Epstein-Barr virus LMP2A.

30 September 2017

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Signaling activities of gammaherpesvirus membrane proteins

30 September 2017

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Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome

30 September 2017

1 reference

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A model for persistent infection with Epstein-Barr virus: the stealth virus of human B cells

30 September 2017

1 reference

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Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis

30 September 2017

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Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection

30 September 2017

1 reference

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Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus

30 September 2017

1 reference

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Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus.

30 September 2017

1 reference

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Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8(+) T lymphocytes.

30 September 2017

1 reference

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Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus

30 September 2017

1 reference

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Epithelial cell adhesion to extracellular matrix proteins induces tyrosine phosphorylation of the Epstein-Barr virus latent membrane protein 2: a role for C-terminal Src kinase.

30 September 2017

1 reference

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B cells regulate murine gammaherpesvirus 68 latency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Non-antigen-specific B-cell activation following murine gammaherpesvirus infection is CD4 independent in vitro but CD4 dependent in vivo.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Complete sequence and genomic analysis of murine gammaherpesvirus 68

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Latency, without persistence, of murine cytomegalovirus in the spleen and kidney.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Identification of Lck-binding elements in tip of herpesvirus saimiri

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Tuning into immunological dissonance: an experimental model for infectious mononucleosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Early events in Epstein-Barr virus infection provide a model for B cell activation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Ecology of the murine alphaherpesvirus and its isolation from lungs of rodents in cell culture.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Pathogenesis of acute and persistent murine herpesvirus infection in mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Comparison of genetic variability at multiple loci across the genomes of the major subtypes of Kaposi's sarcoma-associated herpesvirus reveals evidence for recombination and for two distinct types of open reading frame K15 alleles at the right-hand e

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268483

Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis

21 October 2018

1 reference

12 December 2020

Isolation of five strains of herpesviruses from two species of free living small rodents

1 reference

12 December 2020

Virological and pathological features of mice infected with murine gamma-herpesvirus 68

1 reference

12 December 2020

Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo

1 reference

12 December 2020

Interactions of the murine gammaherpesvirus with the immune system

1 reference

12 December 2020

Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.02234-07

1 reference

14 August 2017

1 reference

14 August 2017

1 reference