Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2'-hydroxyphenyl)benzoxazole analogs of UK-1 (Q36498990)

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27 December 2019

title

Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2'-hydroxyphenyl)benzoxazole analogs of UK-1 (English)

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2

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27 December 2019

author name string

Mireya L McKee

series ordinal

1

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language of work or name

English

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publication date

12 November 2007

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Bioorganic & Medicinal Chemistry

27 December 2019

published in

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volume

16

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27 December 2019

issue

4

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page(s)

1775-1783

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Evaluation of metal-mediated DNA binding of benzoxazole ligands by electrospray ionization mass spectrometry

27 December 2019

cites work

1 reference

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Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles

30 September 2017

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Metal complexes in medicinal chemistry: new vistas and challenges in drug design

30 September 2017

1 reference

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Metal complex-DNA interactions: from transcription inhibition to photoactivated cleavage

30 September 2017

1 reference

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Anticancer metal compounds in NCI's tumor-screening database: putative mode of action

30 September 2017

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Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity

30 September 2017

1 reference

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Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry

30 September 2017

1 reference

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Iron chelators from mycobacteria (1954-1999) and potential therapeutic applications

30 September 2017

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Evaluation of complexes of DNA duplexes and novel benzoxazoles or benzimidazoles by electrospray ionization mass spectrometry

30 September 2017

1 reference

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Ni(II).Arg-Gly-His-DNA interactions: investigation into the basis for minor-groove binding and recognition

28 June 2018

1 reference

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Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1.

21 September 2018

1 reference

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AJI9561, a new cytotoxic benzoxazole derivative produced by Streptomyces sp.

21 September 2018

1 reference

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UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

21 September 2018

1 reference

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Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs

21 September 2018

1 reference

12 December 2020

Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex

1 reference

12 December 2020

UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. III. Antibacterial action of demethyl UK-1

1 reference

12 December 2020

Mg 2+ -mediated binding of 6-Substituted quinolones to DNA: relevance to biological activity

1 reference

12 December 2020

Metal ion-directed cooperative DNA binding of small molecules

1 reference

12 December 2020

10.1016/J.BMC.2007.11.019

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18037301%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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27 December 2019

PubMed publication ID

18037301

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