MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. (Q36500392)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

pilocytic astrocytoma

1 reference

1 reference

1 reference

4

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18 February 2020

Matthias A. Karajannis

5

1 reference

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18 February 2020

David H. Gutmann

7

1 reference

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18 February 2020

8

Charles G Eberhart

1 reference

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18 February 2020

author name string

Cheng-Ying Ho

1

1 reference

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18 February 2020

Eli Bar

2

1 reference

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18 February 2020

Caterina Giannini

3

1 reference

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18 February 2020

David Zagzag

6

1 reference

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18 February 2020

Fausto J Rodriguez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

language of work or name

1 reference

15 November 2012

1 reference

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18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

15

1 reference

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18 February 2020

issue

1

1 reference

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18 February 2020

page(s)

69-82

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Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

18 February 2020

cites work

1 reference

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MAPK pathway activation in pilocytic astrocytoma

30 September 2017

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BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.

30 September 2017

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Identification of microRNAs as potential prognostic markers in ependymoma

30 September 2017

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An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma

30 September 2017

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Grade-specific expression profiles of miRNAs/mRNAs and docking study in human grade I-III astrocytomas

30 September 2017

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Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome

30 September 2017

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Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma

30 September 2017

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NFIB is a potential target for estrogen receptor-negative breast cancers

30 September 2017

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Nuclear factor I/B is an oncogene in small cell lung cancer

30 September 2017

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Identification of transcriptional regulatory networks specific to pilocytic astrocytoma.

30 September 2017

1 reference

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Regulation of PBX3 expression by androgen and Let-7d in prostate cancer

30 September 2017

1 reference

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miRNA signature of schwannomas: possible role(s) of "tumor suppressor" miRNAs in benign tumors

30 September 2017

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Gene expression pathways of high grade localized prostate cancer

30 September 2017

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Survey of MicroRNA expression in pediatric brain tumors

30 September 2017

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miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways

30 September 2017

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PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma

30 September 2017

1 reference

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MicroRNA-21 overexpression contributes to vestibular schwannoma cell proliferation and survival

30 September 2017

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Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas

30 September 2017

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30 September 2017

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Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.

30 September 2017

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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

30 September 2017

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MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

30 September 2017

1 reference

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Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.

30 September 2017

1 reference

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Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes

30 September 2017

1 reference

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Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

30 September 2017

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MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G.

30 September 2017

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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

30 September 2017

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MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells

30 September 2017

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hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

30 September 2017

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The impact of microRNAs on protein output

30 September 2017

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MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

30 September 2017

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

30 September 2017

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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma

30 September 2017

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Expression of FOXP2 in the developing monkey forebrain: comparison with the expression of the genes FOXP1, PBX3, and MEIS2.

30 September 2017

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MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

30 September 2017

1 reference

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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534421

Gliomas in neurofibromatosis type 1: a clinicopathologic study of 100 patients.

30 September 2017

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MicroRNA involvement in brain tumors: from bench to bedside

30 September 2017

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Pbx3 is required for normal locomotion and dorsal horn development

30 September 2017

1 reference

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Methionine aminopeptidase 2 over-expressed in cholangiocarcinoma: potential for drug target

30 September 2017

1 reference

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Effect of BRAFV600E mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model

30 September 2017

1 reference

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Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458.

30 September 2017

1 reference

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Methionine aminopeptidase 2 and cancer

30 September 2017

1 reference

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Extensive modulation of a set of microRNAs in primary glioblastoma

30 September 2017

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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

30 September 2017

1 reference

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miRNAs, cancer, and stem cell division

30 September 2017

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MicroRNA expression profiles classify human cancers

30 September 2017

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Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis

30 September 2017

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

30 September 2017

1 reference

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Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases

30 September 2017

1 reference

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Pbx3 deficiency results in central hypoventilation

30 September 2017

1 reference

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Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity

30 September 2017

1 reference

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Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534421

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534421

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

30 September 2017

1 reference

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Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534421

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534421

Direct and sensitive miRNA profiling from low-input total RNA.

28 June 2018

1 reference

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Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma

28 June 2018

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Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

28 June 2018

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Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers

28 June 2018

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Anaplasia in pilocytic astrocytoma predicts aggressive behavior.

21 September 2018

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Molecular characterization of the intercalated cell masses of the amygdala: implications for the relationship with the striatum.

21 September 2018

1 reference

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Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma

21 September 2018

1 reference

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Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin.

21 September 2018

1 reference

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Nonrandom chromosomal gains in pilocytic astrocytomas of childhood.

21 September 2018

1 reference

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Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23161775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MicroRNA expression profiling for molecular classification of pediatric brain tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23161775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NEUONC/NOS269

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23161775%20AND%20SRC:MED&resulttype=core&format=json