Biochemistry, physiology, and complications of blood doping: facts and speculation (Q36504354)

14 August 2017

1 reference

title

Biochemistry, physiology, and complications of blood doping: facts and speculation (English)

1 reference

14 August 2017

1

Giuseppe Lippi

1 reference

14 August 2017

2

Massimo Franchini

1 reference

14 August 2017

3

Gian Luca Salvagno

1 reference

14 August 2017

4

Gian Cesare Guidi

1 reference

14 August 2017

1 January 2006

1 reference

Critical Reviews in Clinical Laboratory Sciences

14 August 2017

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14 August 2017

43

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14 August 2017

349-391

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14 August 2017

4

1 reference

Sport, physical activity and social exclusion

14 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Challenges in understanding the influence of maximal power training on improving athletic performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Drug use and abuse in sport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Drugs for increasing oxygen and their potential use in doping: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Skeletal muscle glucose uptake during exercise: how is it regulated?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A model of oxygen uptake kinetics in response to exercise: including a means of calculating oxygen demand/deficit/debt

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Blood volume, aerobic power, and endurance performance: potential ergogenic effect of volume loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Managing recalls and withdrawals of blood components

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Fresh blood product manufacture, issue, and use: a chain of diminishing returns?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The use of haemostatic drugs in haemophilia: desmopressin and antifibrinolytic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The role of granulocyte transfusions in neutropenic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Blood pack fault monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Autologous blood donation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Risks of transfusion-transmitted infections: 2003.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Tissue safety in view of CJD and variant CJD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Advances in screening test development for transmissible spongiform encephalopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

In search of the transfusion threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Current status of transfusion triggers for red blood cell concentrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The efficacy of ergogenic agents in athletic competition. Part II: Other performance-enhancing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cloning and expression of human erythropoietin cDNA in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

VO2MAX, blood doping, and erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Detection of DNA-recombinant human epoetin-alfa as a pharmacological ergogenic aid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin: physico- and biochemical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin gene expression in human, monkey and murine brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Pharmacokinetics/Pharmacodynamics of Recombinant Human Erythropoietins in Doping Control1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Pharmacokinetic-pharmacodynamic modelling of recombinant human erythropoietin in athletes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Faster oxygen uptake kinetics at the onset of submaximal cycling exercise following 4 weeks recombinant human erythropoietin (r-HuEPO) treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Differentiating factors between erythropoiesis-stimulating agents: a guide to selection for anaemia of chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Control of rHuEPO biological activity: the role of carbohydrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cellular mechanism of oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Oxygen-sensitive ion channels: how ubiquitous are they?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A novel oxygen-sensitive potassium current in rat carotid body type I cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Oxygen and glucose sensing by carotid body glomus cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cell biology. How cells endure low oxygen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Benefits and concerns of treating pre-dialysis and renal transplant patients with recombinant human erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The decision to prematurely terminate a trial of R-HuEPO due to thrombotic events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin-associated hypertensive posterior leukoencephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Pure red-cell aplasia and epoetin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Acquired red cell aplasia in association with the use of recombinant erythropoietin in chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Recommendations on haematological criteria for the diagnosis of epoetin-induced pure red cell aplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cessation of intensive treatment with recombinant human erythropoietin is followed by secondary anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin regulates tumour growth of human malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Laboratory screening for erythropoietin abuse in sport: an emerging challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Strategies for rhEPO detection in sport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Stability of blood cell counts, hematologic parameters and reticulocytes indexes on the Advia A120 hematologic analyzer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Detection of recombinant human erythropoietin in urine by isoelectric focusing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Detection of isoelectric profiles of erythropoietin in urine: differentiation of natural and administered recombinant hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Improved capillary isoelectric focusing method for recombinant erythropoietin analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Reticulocyte cellular indices: a new approach in the diagnosis of anemias and monitoring of erythropoietic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A new principle suggested for detection of darbepoetin-alpha (NESP) doping

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Altitude and endurance training

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Tibetans at extreme altitude

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Determinants of erythropoietin release in response to short-term hypobaric hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

VO2max and haemoglobin mass of trained athletes during high intensity training.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Medicine and mechanisms in altitude sickness. Recommendations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Consensus statement on chronic and subacute high altitude diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Neocytolysis: physiological down-regulator of red-cell mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The negative regulation of red cell mass by neocytolysis: physiologic and pathophysiologic manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin withdrawal leads to the destruction of young red cells at the endothelial-macrophage interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Apoptotic mechanisms in the control of erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The effect of altitude on cycling performance: a challenge to traditional concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Effects of intermittent hypoxic training on aerobic and anaerobic performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A practical approach to altitude training: where to live and train for optimal performance enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Effects of intermittent exposure to high altitude on blood volume and erythropoietic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Intermittent normobaric hypoxia does not alter performance or erythropoietic markers in highly trained distance runners

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin acute reaction and haematological adaptations to short, intermittent hypobaric hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

The influence of intermittent altitude exposure to 4100 m on exercise capacity and blood variables.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Intermittent hypoxia research in the former soviet union and the commonwealth of independent States: history and review of the concept and selected applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Intermittent hypoxic training: fact and fancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Current trends in altitude training

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Pre-acclimatization to high altitude using exercise with normobaric hypoxic gas mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Effects of altitude on mood, behaviour and cognitive functioning. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

What happened to blood substitutes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Pulmonary applications of perfluorochemical liquids: ventilation and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Understanding the fundamentals of perfluorocarbons and perfluorocarbon emulsions relevant to in vivo oxygen delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Genotoxicity of hyperbaric oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Perfluorocarbons in the twenty-first century: clinical applications as transfusion alternatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Survival of Mammals Breathing Organic Liquids Equilibrated with Oxygen at Atmospheric Pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Characterization and mechanism of side-effects of Oxygent HT (highly concentrated fluorocarbon emulsion) in swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Effects of single and multiple doses of perfluorocarbon in comparison with continuous partial liquid ventilation on gas exchange and lung pathology in newborn surfactant-depleted pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Breathing gas perfluorocarbon measurements using an absorber filled with zeolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Doping with artificial oxygen carriers: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Artificial O2 carriers: status in 2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Oxidized mono-, di-, tri-, and polysaccharides as potential hemoglobin cross-linking reagents for the synthesis of high oxygen affinity artificial blood substitutes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

A recombinant polymeric hemoglobin with conformational, functional, and physiological characteristics of an in vivo O2transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Recombinant hemoglobins with low oxygen affinity and high cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Chemical characterization of pyridoxalated hemoglobin polyoxyethylene conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Artificial oxygen carriers as red blood cell substitutes: a selected review and current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Insights from studies of blood substitutes in trauma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Rate of NO scavenging alters effects of recombinant hemoglobin solutions on pulmonary vasoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

O-raffinose-polymerised haemoglobin. A biochemical and pharmacological profile of an oxygen carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Detection of hemoglobin-based oxygen carriers in human serum for doping analysis: confirmation by size-exclusion HPLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Allosteric modulators: the new generation of receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Increased oxygenation of intracranial tumors by efaproxyn (efaproxiral), an allosteric hemoglobin modifier: In vivo EPR oximetry study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Synthesis and X-ray studies of chiral allosteric modifiers of hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

RSR13, a potential athletic performance enhancement agent: detection in urine by gas chromatography/mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Iron homeostasis and inherited iron overload disorders: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Utility of hematological and iron-related screening in elite athletes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Iron Supplementation in Athletes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Abnormally high serum ferritin levels among professional road cyclists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Iron supplementation in athletes--first do no harm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Serum ferritin and risk of the metabolic syndrome in U.S. adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Mutations in the hereditary haemochromatosis gene HFE in professional endurance athletes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Cobalt chloride administration in athletes: a new perspective in blood doping?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Gene manipulation and improvement of athletic performances: new strategies in blood doping

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

21 January 2018

Gene doping in sports

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Doping in the recombinant era: strategies and counterstrategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin gene therapy leads to autoimmune anemia in macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Expression of erythropoietin in cats treated with a recombinant adeno-associated viral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Human erythropoietin gene therapy for patients with chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Medicine. Gene therapy--new challenges ahead

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Recent developments in gene transfer: risk and ethics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

What makes clinical research ethical?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin abuse and erythropoietin gene doping: detection strategies in the genomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Polyclonal long-term repopulating stem cell clones in a primate model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Blood doping and related issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Identification of the renal erythropoietin-producing cells using transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Modeling of Oxygen Transport in Blood-Perfluorocarbon Emulsion Mixtures Part II

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Hemoglobin-based oxygen carrier preserves submaximal exercise capacity in humans*

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Oxygen sensing in airway chemoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

Erythropoietin abuse in athletes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360600755313

10.1080/10408360600755313

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16769597