Neuregulin mediates F-actin-driven cell migration through inhibition of protein kinase D1 via Rac1 protein (Q36508683)

14 August 2017

Neuregulin mediates F-actin-driven cell migration through inhibition of protein kinase D1 via Rac1 protein (English)

1 reference

14 August 2017

Heike Döppler

1

1 reference

14 August 2017

Ligia I Bastea

series ordinal

2

1 reference

14 August 2017

Tim Eiseler

series ordinal

3

1 reference

14 August 2017

Peter Storz

series ordinal

4

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14 August 2017

language of work or name

English

0 references

publication date

12 November 2012

1 reference

Journal of Biological Chemistry

14 August 2017

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14 August 2017

288

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14 August 2017

1

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14 August 2017

455-465

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describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3537043/fullTextXML

inferred from PubMed Central ID database lookup

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Reactive oxygen species regulate a slingshot-cofilin activation pathway

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Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

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Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion

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Loss of cell-cell contacts induces NF-kappaB via RhoA-mediated activation of protein kinase D1

30 September 2017

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Role of heregulin in human cancer

30 September 2017

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The cofilin pathway in breast cancer invasion and metastasis

30 September 2017

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Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis

30 September 2017

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The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors

30 September 2017

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30 September 2017

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Cofilin phosphatases and regulation of actin dynamics

30 September 2017

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Neuregulins 1-4 are expressed in the cytoplasm or nuclei of ductal carcinoma (in situ) of the human breast

30 September 2017

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Protein kinase D signaling

30 September 2017

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Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

30 September 2017

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Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

30 September 2017

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Development of an autocrine neuregulin signaling loop with malignant transformation of human breast epithelial cells

30 September 2017

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A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia

30 September 2017

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Neuregulins: functions, forms, and signaling strategies

30 September 2017

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Protein kinase D mediates a stress-induced NF-kappaB activation and survival pathway

30 September 2017

1 reference

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Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

30 September 2017

1 reference

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Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation

30 September 2017

1 reference

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Heregulin regulates the actin cytoskeleton and promotes invasive properties in breast cancer cell lines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

30 September 2017

1 reference

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Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Putting a new twist on actin: ADF/cofilins modulate actin dynamics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Involvement of heregulin-beta2 in the acquisition of the hormone-independent phenotype of breast cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Regulation of NADPH oxidase activity by Rac GTPase activating protein(s).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

The breast proto-oncogene, HRGalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Pathogenesis of Paget's disease: epidermal heregulin-alpha, motility factor, and the HER receptor family

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3537043

Protein kinase C mu is down-regulated in androgen-independent prostate cancer

21 September 2018

1 reference

12 December 2020

Bidirectional interactions between the estrogen receptor and the cerbB-2 signaling pathways: heregulin inhibits estrogenic effects in breast cancer cells

1 reference

12 December 2020

NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice

1 reference

12 December 2020

Neu differentiation factor induces ErbB2 down-regulation and apoptosis of ErbB2-overexpressing breast tumor cells

1 reference

12 December 2020

Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.397448

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

23148218

1 reference