Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator. (Q36510038)

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scientific article published on 28 January 2008

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English	Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.	scientific article published on 28 January 2008

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scholarly article

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1 January 2020

Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator (English)

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1 January 2020

cystic fibrosis

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transmembrane protein

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4

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1 January 2020

Margarida Duarte Amaral

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1 January 2020

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A Schmidt

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1 January 2020

L K Hughes

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1 January 2020

Z Cai

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H Li

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1 January 2020

D N Sheppard

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28 January 2008

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1 January 2020

British Journal of Pharmacology

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1 January 2020

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1 January 2020

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1 January 2020

1311-1323

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1 January 2020

Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis.

1 reference

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30 September 2017

Domain interdependence in the biosynthetic assembly of CFTR.

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30 September 2017

Specific rescue of cystic fibrosis transmembrane conductance regulator processing mutants using pharmacological chaperones

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30 September 2017

The ABC protein turned chloride channel whose failure causes cystic fibrosis

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30 September 2017

Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules

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30 September 2017

Differential sensitivity of the cystic fibrosis (CF)-associated mutants G551D and G1349D to potentiators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel

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30 September 2017

Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies.

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30 September 2017

Cystic fibrosis

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30 September 2017

Processing of CFTR: traversing the cellular maze--how much CFTR needs to go through to avoid cystic fibrosis?

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30 September 2017

Binding site of activators of the cystic fibrosis transmembrane conductance regulator in the nucleotide binding domains.

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30 September 2017

The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors

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30 September 2017

Pharmacological chaperones: potential treatment for conformational diseases.

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30 September 2017

Direct block of the cystic fibrosis transmembrane conductance regulator Cl(-) channel by niflumic acid

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30 September 2017

On the mechanism of MgATP-dependent gating of CFTR Cl- channels

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Genistein modifies the activation kinetics and magnitude of phosphorylated wild-type and G551D-CFTR chloride currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

1 reference

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30 September 2017

Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Molecular pharmacology of the CFTR Cl- channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Activation of DeltaF508 CFTR in an epithelial monolayer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

Mechanism of glibenclamide inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a murine cell line

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30 September 2017

Tolbutamide causes open channel blockade of cystic fibrosis transmembrane conductance regulator Cl- channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

CFTR displays voltage dependence and two gating modes during stimulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275442

30 September 2017

ATP alters current fluctuations of cystic fibrosis transmembrane conductance regulator: evidence for a three-state activation mechanism

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30 September 2017

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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30 September 2017

Sodium-specific membrane channels of frog skin are pores: current fluctuations reveal high turnover

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30 September 2017

Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers

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30 September 2017

The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

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28 June 2018

Use and specificity of genistein as inhibitor of protein-tyrosine kinases

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28 June 2018

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

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28 June 2018

Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids

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21 September 2018

Capsaicin potentiates wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride-channel currents

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21 September 2018

Genistein Can Modulate Channel Function by a Phosphorylation-Independent Mechanism: Importance of Hydrophobic Mismatch and Bilayer Mechanics

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21 September 2018

Inhibition of ATPase, GTPase and adenylate kinase activities of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator by genistein.

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21 September 2018

Regulation of murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in Chinese hamster ovary cells.

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21 September 2018

Genistein potentiates wild-type and delta F508-CFTR channel activity

1 reference

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21 September 2018

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

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21 September 2018

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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21 September 2018

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

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Structure and function of the CFTR chloride channel

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7 January 2021

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10.1038/SJ.BJP.0707663

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