Histone deacetylation as a target for radiosensitization (Q36510514)

14 August 2017

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title

Histone deacetylation as a target for radiosensitization (English)

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14 August 2017

David Cerna

1

1 reference

PubMed ID

16782459

14 August 2017

Kevin Camphausen

series ordinal

2

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PubMed ID

16782459

14 August 2017

Philip J Tofilon

series ordinal

3

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14 August 2017

1 January 2006

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Current Topics in Developmental Biology

14 August 2017

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14 August 2017

73

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14 August 2017

173-204

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ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

14 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Effects of nucleoside analogs and sodium butyrate on recovery from potentially lethal X ray damage in human colon tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Selective growth inhibition of tumor cells by a novel histone deacetylase inhibitor, NVP-LAQ824.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Chemical agents that promote chromatin compaction radiosensitize tumour cells

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The many HATs of transcription coactivators

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Enhanced radiation-induced cell killing and prolongation of gammaH2AX foci expression by the histone deacetylase inhibitor MS-275.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The diverse functions of histone acetyltransferase complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

A transcriptional co-repressor that interacts with nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Modulation of radiation response by histone deacetylase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylases, transcriptional control, and cancer

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Prospects: histone deacetylase inhibitors

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Clinical development of histone deacetylase inhibitors as anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Kinetics of histone hyperacetylation and deacetylation in human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Binary switches and modification cassettes in histone biology and beyond.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The human histone deacetylase family

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Coordination of DNA damage responses via the Smc5/Smc6 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

An epigenetic code for DNA damage repair pathways?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Molecular biology. Chromatin higher order folding--wrapping up transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Identification of novel isoform-selective inhibitors within class I histone deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

HDAC6 is a microtubule-associated deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Susceptibility and radiosensitization of human glioblastoma cells to trichostatin A, a histone deacetylase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone acetylases and deacetylases in cell proliferation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Roles of histone acetyltransferases and deacetylases in gene regulation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

ATM signaling and genomic stability in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Effects of Sodium Butyrate and 3-Aminobenzamide on Survival of Chinese Hamster HA-1 Cells after X Irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Crystal structure of the nucleosome core particle at 2.8 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Valproic acid alters chromatin structure by regulation of chromatin modulation proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone acetyltransferases: function, structure, and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Nuclear receptor coregulators: cellular and molecular biology

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Clinical pharmacology of sodium butyrate in patients with acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone Deacetylase Inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitors radiosensitize human melanoma cells by suppressing DNA repair activity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Persistent interactions of core histone tails with nucleosomal DNA following acetylation and transcription factor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Effect of polar organic compounds on leukemic cells. Butyrate-induced partial remission of acute myelogenous leukemia in a child.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Mammalian histone acetyltransferases and their complexes

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Phase I study of oral CI-994 in combination with carboplatin and paclitaxel in the treatment of patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The role of corepressors in transcriptional regulation by nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The nucleosome core all wrapped up

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Pathways of DNA double-strand break repair during the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylases (HDACs): characterization of the classical HDAC family

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Effects of FK228, a novel histone deacetylase inhibitor, on tumor growth and expression of p21 and c-myc genes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

An increasingly complex code

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Acetylation of histones and transcription-related factors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

The language of covalent histone modifications

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Synthesis and histone deacetylase inhibitory activity of new benzamide derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Reversible effects of Na-butyrate on histone acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitors in cancer treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Clinical research in pancreatic cancer: the Radiation Therapy Oncology Group trials

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Targeting chromatin disruption: Transcription regulators that acetylate histones

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase as a new target for cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Cell cycle regulation of chromatin at an origin of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

Inhibition of repair of X-ray-induced DNA double-strand breaks in human lymphocytes exposed to sodium butyrate

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973006-4

7 January 2021

10.1016/S0070-2153(05)73006-4

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16782459