Methylation and Immunoexpression of p16(INK4a) Tumor Suppressor Gene in Primary Breast Cancer Tissue and Their Quantitative p16(INK4a) Hypermethylation in Plasma by Real-Time PCR. (Q36518767)

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scientific article published on 26 December 2012

Language	Label	Description	Also known as
English	Methylation and Immunoexpression of p16(INK4a) Tumor Suppressor Gene in Primary Breast Cancer Tissue and Their Quantitative p16(INK4a) Hypermethylation in Plasma by Real-Time PCR.	scientific article published on 26 December 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Methylation and Immunoexpression of p16(INK4a) Tumor Suppressor Gene in Primary Breast Cancer Tissue and Their Quantitative p16(INK4a) Hypermethylation in Plasma by Real-Time PCR. (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

hypermethylation

1 reference

based on heuristic

inferred from title

author name string

Jae Jun Lee

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Eunkyung Ko

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Junhun Cho

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Ha Young Park

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jeong Eon Lee

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Seok Jin Nam

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Duk-Hwan Kim

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Eun Yoon Cho

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

publication date

26 December 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Korean journal of pathology

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

46

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Europe PubMed Central

PMC publication ID

14 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

554-561

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

DNA methylation in colorectal cancer--impact on screening and therapy monitoring modalities?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

p16(INK4a) promoter methylation and protein expression in breast fibroadenoma and carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

Alterations of p16(INK4a) and p14(ARF) in patients with severe oral epithelial dysplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

Aberrant cytoplasmic expression of the p16 protein in breast cancer is associated with accelerated tumour proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

Prognostic and predictive factors in breast cancer by immunohistochemical analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

High frequency of aberrant p16(INK4A) expression in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

30 September 2017

p53 Deficiency leads to compensatory up-regulation of p16INK4a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Methylation of CpG islands of p16(INK4a) and cyclinD1 overexpression associated with progression of intraductal proliferative lesions of the breast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

The clinical importance of Ki-67, p16, p14, and p57 expression in patients with advanced ovarian carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

P16INK4a protein expression is associated with poor survival of the breast cancer patients after CMF chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

Preferential loss of expression of p16(INK4a) rather than p19(ARF) in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540333

21 September 2018

INK4a gene expression and methylation in primary breast cancer: overexpression of p16INK4a messenger RNA is a marker of poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential frequencies of p16(INK4a) promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoblastoma and p16 proteins in mammary carcinoma: their relationship to cyclin D1 and histopathological parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of cell cycle regulators Cyclin D1, p14, p16, CDK4 and Rb in nodular melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible associations among expression of p14(ARF), p16(INK4a), p21(WAF1/CIP1), p27(KIP1), and p53 accumulation and the balance of apoptosis and cell proliferation in ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cell cycle-regulatory proteins rb, p16/MTS1, p27/KIP1, p21/WAF1, cyclin D1 and cyclin E in breast cancer: correlations with expression of activating protein-1 family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the p16(Ink4a) tumor suppressor gene 5'-CpG island in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23323106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4132/KOREANJPATHOL.2012.46.6.554

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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