A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors (Q36520764)

14 August 2017

A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors (English)

1 reference

14 August 2017

1 reference

Zhongling Zhu

1

1 reference

14 August 2017

Zhengzi Qian

2

1 reference

14 August 2017

Zhao Yan

3

1 reference

14 August 2017

Cuicui Zhao

4

1 reference

14 August 2017

Huaqing Wang

5

1 reference

14 August 2017

Guoguang Ying

6

1 reference

14 August 2017

language of work or name

English

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publication date

4 January 2013

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International Journal of Nanomedicine

14 August 2017

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14 August 2017

8

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14 August 2017

129-136

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Creative Commons Attribution-NonCommercial 3.0 Unported

14 August 2017

start time

1 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells.

1 reference

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Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway

30 September 2017

1 reference

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Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

30 September 2017

1 reference

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Clinically useful anticancer, antitumor, and antiwrinkle agent, ursolic acid and related derivatives as medicinally important natural product

30 September 2017

1 reference

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Antiangiogenic activity of ursolic acid.

30 September 2017

1 reference

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Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro

30 September 2017

1 reference

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Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells

30 September 2017

1 reference

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Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells

30 September 2017

1 reference

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Oleanolic acid and ursolic acid: research perspectives

30 September 2017

1 reference

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LC-MS determination and pharmacokinetic studies of ursolic acid in rat plasma after administration of the traditional chinese medicinal preparation Lu-Ying extract

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Nanosizing: a formulation approach for poorly-water-soluble compounds

30 September 2017

1 reference

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Ursolic acid: an anti-tumorigenic and chemopreventive activity. Minireview

30 September 2017

1 reference

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Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Pharmacology of oleanolic acid and ursolic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540956

Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells

21 September 2018

1 reference

12 December 2020

Quantitation of ursolic acid in human plasma by ultra performance liquid chromatography tandem mass spectrometry and its pharmacokinetic study

1 reference

12 December 2020

Development of a liquid chromatography-mass spectrometry method for the determination of ursolic acid in rat plasma and tissue: application to the pharmacokinetic and tissue distribution study

1 reference

12 December 2020

Intracellular Ca2+ release mediates ursolic acid-induced apoptosis in human leukemic HL-60 cells

1 reference

12 December 2020

Apoptotic activity of ursolic acid may correlate with the inhibition of initiation of DNA replication

1 reference

12 December 2020

Identifiers

DOI

10.2147/IJN.S38271

1 reference

14 August 2017

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14 August 2017

PubMed publication ID

23319864

1 reference