The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals. (Q36522635)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1

J Thomas Sanderson

2 references

14 August 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

publication date

28 June 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

published in

Toxicological Sciences

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

3-21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro

26 December 2019

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The inhibition of human prostatic aromatase activity by imidazole drugs including ketoconazole and 4-hydroxyandrostenedione.

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Distribution of methyl sulfone metabolites of polychlorinated biphenyls and p,p'-DDE in human tissues

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Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro

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Atrazine disrupts the hypothalamic control of pituitary-ovarian function

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Role of steroidogenic factor 1 and aromatase in temperature-dependent sex determination in the red-eared slider turtle.

21 January 2018

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Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison

21 January 2018

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Colocalization of P450c17 and cytochrome b5 in androgen-synthesizing tissues of the human.

21 January 2018

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Effects of some persistent halogenated environmental contaminants on aromatase (CYP19) activity in the human choriocarcinoma cell line JEG-3.

21 January 2018

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Aromatase enzyme activity and sex determination in chickens

21 January 2018

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Factors affecting mammary tumor incidence in chlorotriazine-treated female rats: hormonal properties, dosage, and animal strain

21 January 2018

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Mechanism of toxic action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in cultured human luteinized granulosa cells

21 January 2018

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Human adrenal CYP11B1: localization by in situ-hybridization and functional expression in cell cultures

21 January 2018

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Testicular cytochrome P450scc and LHR as possible targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the mouse

21 January 2018

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A risk assessment of atrazine use in California: human health and ecological aspects

21 January 2018

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Toxic equivalency factors of polychlorinated dibenzo-p-dioxins in an ovulation model: validation of the toxic equivalency concept for one aspect of endocrine disruption.

21 January 2018

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Multiple signal transduction pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase in normal and tumoral target tissues

21 January 2018

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Effects of environmental antiandrogens on reproductive development in experimental animals

21 January 2018

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Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat.

21 January 2018

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Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida

21 January 2018

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Herbicides: feminization of male frogs in the wild

21 January 2018

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Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses

21 January 2018

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Plasma concentrations of estradiol and testosterone, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis exposed to estradiol or atrazine

21 January 2018

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Inhibition of aromatase activity by methyl sulfonyl PCB metabolites in primary culture of human mammary fibroblasts.

21 January 2018

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A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase

21 January 2018

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Assessment of the effects of chemicals on the expression of ten steroidogenic genes in the H295R cell line using real-time PCR.

21 January 2018

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Quantitative evidence for global amphibian population declines

21 January 2018

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ACTH regulation of cholesterol movement in isolated adrenal cells

21 January 2018

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Structure-activity relationship for inhibition of CYP11B1-dependent glucocorticoid synthesis in Y1 cells by aryl methyl sulfones.

21 January 2018

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Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line

21 January 2018

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2,3,7,8-Tetrachlorodibenzo-p-dioxin reduces the number, size, and organelle content of Leydig cells in adult rat testes.

21 January 2018

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In vitro bioactivation of the environmental pollutant 3-methylsulphonyl-2, 2-bis(4-chlorophenyl)-1,1-dichloroethene in the human adrenal gland.

21 January 2018

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Genetic and hormonal factors in sex differentiation of the brain

21 January 2018

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Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans.

21 January 2018

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Antiandrogens as environmental endocrine disruptors.

21 January 2018

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Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism

21 January 2018

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Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites.

21 January 2018

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Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist

21 January 2018

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Environmental antiandrogens: developmental effects, molecular mechanisms, and clinical implications

21 January 2018

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Effects of organochlorine compounds on cytochrome P450 aromatase activity in an immortal sea turtle cell line

21 January 2018

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Triazine herbicide exposure and breast cancer incidence: an ecologic study in Kentucky counties

21 January 2018

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Brain aromatase in Japanese medaka (Oryzias latipes): Molecular characterization and role in xenoestrogen-induced sex reversal

21 January 2018

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Cerebral and gonadal aromatase expressions are differently affected during sex differentiation of Pleurodeles waltl

21 January 2018

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Identification of enzymes involved in the metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in human liver microsomes

21 January 2018

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Enantiomeric specificity of methylsulfonyl-PCBs and distribution of bis(4-chlorophenyl) sulfone, PCB, and DDE methyl sulfones in grey seal tissues

21 January 2018

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Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine

21 January 2018

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The effects of atrazine on female wistar rats: an evaluation of the protocol for assessing pubertal development and thyroid function.

21 January 2018

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Synergistic activation of the human type II 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase promoter by the transcription factor steroidogenic factor-1/adrenal 4-binding protein and phorbol ester

21 January 2018

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Effects of bisphenol A-related diphenylalkanes on vitellogenin production in male carp (Cyprinus carpio) hepatocytes and aromatase (CYP19) activity in human H295R adrenocortical carcinoma cells

21 January 2018

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Cytotoxicity and aromatase (CYP19) activity modulation by organochlorines in human placental JEG-3 and JAR choriocarcinoma cells.

21 January 2018

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Polychlorinated biphenyl 126 stimulates basal and inducible aldosterone biosynthesis of human adrenocortical H295R cells

21 January 2018

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Effects of developmental exposure to 2,2 ,4,4 ,5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in rats

21 January 2018

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Novel involvement of a mitochondrial steroid hydroxylase (P450c11) in xenobiotic metabolism

21 January 2018

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Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase

21 January 2018

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Imidazole antimycotics: selective inhibitors of steroid aromatization and progesterone hydroxylation

21 January 2018

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Diverse mechanisms of control of aromatase gene expression

21 January 2018

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Molecular biology of steroid hormone synthesis

21 January 2018

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Effects of endocrine disrupting chemicals on distinct expression patterns of estrogen receptor, cytochrome P450 aromatase and p53 genes in oryzias latipes liver

21 January 2018

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The role of 17 beta-hydroxysteroid dehydrogenases.

21 January 2018

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2,3,7,8-tetrachlorodibenzo-p-dioxin decreases estradiol production without altering the enzyme activity of cytochrome P450 aromatase of human luteinized granulosa cells in vitro.

21 January 2018

1 reference

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Molecular target of endocrine disruption in human luteinizing granulosa cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin: inhibition of estradiol secretion due to decreased 17alpha-hydroxylase/17,20-lyase cytochrome P450 expression.

21 January 2018

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Evidence of endocrine disruption in the imposex-affected gastropod Bolinus brandaris.

21 January 2018

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A novel nonradioactive method for measuring aromatase activity using a human ovarian granulosa-like tumor cell line and an estrone ELISA.

21 January 2018

1 reference

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Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells

21 January 2018

1 reference

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Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree

21 January 2018

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Adrenal zonation: clues from 11beta-hydroxylase and aldosterone synthase

21 January 2018

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The NCI-H295 cell line: a pluripotent model for human adrenocortical studies

21 January 2018

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Forms and prevalence of intersexuality and effects of environmental contaminants on sexuality in cricket frogs (Acris crepitans).

21 January 2018

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Localization and expression of adrenocorticotropic hormone receptor mRNA in normal and neoplastic human adrenal cortex.

21 January 2018

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Atrazine is a competitive inhibitor of phosphodiesterase but does not affect the estrogen receptor

21 January 2018

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Cellular and biochemical mechanisms by which environmental oestrogens influence reproductive function

21 January 2018

1 reference

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Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes

21 January 2018

1 reference

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2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity?

21 January 2018

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2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells.

21 January 2018

1 reference

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17-alpha-ethinylestradiol affects reproduction, sexual differentiation and aromatase gene expression of the medaka (Oryzias latipes).

21 January 2018

1 reference

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Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family

21 January 2018

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Aromatase--a brief overview

21 January 2018

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An updated review of environmental estrogen and androgen mimics and antagonists.

21 January 2018

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StAR protein and the regulation of steroid hormone biosynthesis

21 January 2018

1 reference

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In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

The effects of atrazine metabolites on puberty and thyroid function in the male Wistar rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Assessment of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture, in the EDSP male and female pubertal protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Developmental expression of genes for the stereoidogenic enzymes P450scc (20,22-desmolase), P450c17 (17 alpha-hydroxylase/17,20-lyase), and P450c21 (21-hydroxylase) in the human fetus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Forskolin up-regulates aromatase (CYP19) activity and gene transcripts in the human adrenocortical carcinoma cell line H295R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Effect of epidermal growth factor and prostaglandin on the expression of aromatase (CYP19) in human adrenocortical carcinoma cell line NCI-H295R cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Inhibition of cytochromes P450 by antifungal imidazole derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL051

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFL051

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16807284%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference