RORalpha, a pivotal nuclear receptor for Purkinje neuron survival and differentiation: from development to ageing (Q36526378)

14 August 2017

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title

RORalpha, a pivotal nuclear receptor for Purkinje neuron survival and differentiation: from development to ageing (English)

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14 August 2017

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Fatiha Boukhtouche

1

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14 August 2017

Mohamed Doulazmi

2

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14 August 2017

Florence Frederic

3

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14 August 2017

Isabelle Dusart

4

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14 August 2017

Bernard Brugg

5

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14 August 2017

Jean Mariani

6

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14 August 2017

language of work or name

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1 January 2006

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14 August 2017

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14 August 2017

5

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14 August 2017

2

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14 August 2017

97-104

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https://scigraph.springernature.com/pub.10.1080/14734220600750184

14 August 2017

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cites work

Staggerer mutant mouse Purkinje cells do not contain detectable calmodulin mRNA.

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12 December 2020

Apoptosis in the aging process

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12 December 2020

Cerebellar Purkinje cell loss during life span of the heterozygous staggerer mouse (Rora(+)/Rora(sg)) is gender-related.

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12 December 2020

A comparative study of Purkinje cells in two RORalpha gene mutant mice: staggerer and RORalpha(-/-).

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12 December 2020

RORA, a large common fragile site gene, is involved in cellular stress response

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12 December 2020

Characterization of the retinoid orphan-related receptor-alpha coactivator binding interface: a structural basis for ligand-independent transcription

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12 December 2020

Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention

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12 December 2020

Coactivators for the orphan nuclear receptor RORalpha

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12 December 2020

Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences

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12 December 2020

Transition from monomeric to homodimeric DNA binding by nuclear receptors: identification of RevErbAalpha determinants required for RORalpha homodimer complex formation

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12 December 2020

Evidence for a hyperexcitability state of staggerer mutant mice macrophages

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12 December 2020

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

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12 December 2020

The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

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12 December 2020

The growth of the dendritic trees of Purkinje cells in irradiated agranular cerebellar cortex

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12 December 2020

Staggerer, a new mutation in the mouse affecting the cerebellum

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12 December 2020

Postnatal cerebellar cells from staggerer mutant mice express embryonic cell surface characteristic

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12 December 2020

Role of staggerer gene in determining cell number in cerebellar cortex. II. Granule cell death and persistence of the external granule cell layer in young mouse chimeras.

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12 December 2020

The structural integrity of ROR alpha isoforms is mutated in staggerer mice: cerebellar coexpression of ROR alpha1 and ROR alpha4.

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12 December 2020

Disruption of the nuclear hormone receptor RORalpha in staggerer mice

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12 December 2020

Decreased number of cells in the inferior olivary nucleus of the developing staggerer mouse.

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12 December 2020

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

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12 December 2020

Abnormal IL-1beta cytokine expression in the cerebellum of the ataxic mutant mice staggerer and lurcher.

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12 December 2020

Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells.

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12 December 2020

Structural elements of an orphan nuclear receptor-DNA complex

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12 December 2020

Increased cerebellar Purkinje cell numbers in mice overexpressing a human bcl-2 transgene.

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12 December 2020

Microglia promote the death of developing Purkinje cells.

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12 December 2020

Permanence and fate of paramembranous synaptic specializations in "mutants" experimental animals.

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12 December 2020

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

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12 December 2020

The nonconserved hinge region and distinct amino-terminal domains of the ROR alpha orphan nuclear receptor isoforms are required for proper DNA bending and ROR alpha-DNA interactions

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12 December 2020

A unified nomenclature system for the nuclear receptor superfamily

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12 December 2020

Sonic hedgehog regulates the growth and patterning of the cerebellum

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12 December 2020

A role for both wild-type and expanded ataxin-7 in transcriptional regulation

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12 December 2020

System-level identification of transcriptional circuits underlying mammalian circadian clocks

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12 December 2020

Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse

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12 December 2020

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

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12 December 2020

Early dendritic development of Purkinje cells in the rat cerebellum. A light and electron microscopic study using axonal tracing in 'in vitro' slices

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12 December 2020

Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice

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12 December 2020

Early postnatal Purkinje cells from staggerer mice undergo aberrant development in vitro with characteristic morphologic and gene expression abnormalities.

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12 December 2020

Enhanced susceptibility of staggerer (RORalphasg/sg) mice to lipopolysaccharide-induced lung inflammation.

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12 December 2020

Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors

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12 December 2020

The Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of Weaver and Staggerer mice

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12 December 2020

Progressive atrophy of cerebellar Purkinje cell dendrites during aging of the heterozygous staggerer mouse (Rora(+/sg)).

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12 December 2020

Quantitative effects of climbing fibre deafferentation on the adult Purkinje cell dendritic tree

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12 December 2020

The nuclear receptor superfamily: the second decade

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12 December 2020

ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development

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12 December 2020

The "CholesteROR" protective pathway in the vascular system

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12 December 2020

Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system.

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12 December 2020

Purkinje cell ontogeny: formation and maintenance of spines.

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12 December 2020

The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1.

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12 December 2020

Purkinje cell fate in staggerer mutants: agenesis versus cell death

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12 December 2020

ROR alpha in genetic control of cerebellum development: 50 staggering years

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12 December 2020

An orphan nuclear receptor, mROR alpha, and its spatial expression in adult mouse brain

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12 December 2020

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12 December 2020

Structural and immunohistological modifications in olfactory bulb of the staggerer mutant mouse.

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12 December 2020

Multiple innervation of cerebellar Purkinje cells by climbing fibres in staggerer mutant mouse

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12 December 2020

Neuronal cell loss in heterozygous staggerer mutant mice: a model for genetic contributions to the aging process.

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12 December 2020

Cerebellar synaptogenesis: what we can learn from mutant mice.

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12 December 2020

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells

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12 December 2020

Purkinje cell loss in heterozygous staggerer mutant mice during aging

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12 December 2020

Cell loss in the inferior olive of the staggerer mutant mouse is an indirect effect of the gene.

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12 December 2020

A qualitative and quantitative light microscopic study of the inferior olivary complex in the adult staggerer mutant mouse.

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12 December 2020

RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers

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12 December 2020

Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor

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12 December 2020

Purkinje cell survival and axonal regeneration are age dependent: an in vitro study.

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12 December 2020

Role of staggerer gene in determining cell number in cerebellar cortex. I. Granule cell death is an indirect consequence of staggerer gene action.

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12 December 2020

Mechanisms of aging: an appraisal of the oxidative stress hypothesis

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12 December 2020

Prominent expression of nuclear hormone receptor ROR alpha in Purkinje cells from early development.

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12 December 2020

Expression and regulation of the nuclear receptor RORalpha in human vascular cells

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12 December 2020

Human retinoic acid receptor-related orphan receptor alpha1 overexpression protects neurones against oxidative stress-induced apoptosis

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12 December 2020

Cell-cell interactions influence survival and differentiation of purified Purkinje cells in vitro.

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12 December 2020

Orphan nuclear receptors: from gene to function

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12 December 2020

Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer.

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12 December 2020

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12 December 2020

Electron microscopic analysis of postnatal histogenesis in the cerebellar cortex of staggerer mutant mice

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12 December 2020

Staggerer chimeras: Intrinsic nature of purkinje cell defects and implications for normal cerebellar development

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12 December 2020

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

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12 December 2020

Decreased number of cells in the inferior olivary nucleus of the adult mouse (+/sg) heterozygous for the staggerer gene

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12 December 2020

RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways

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12 December 2020

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12 December 2020

Implication of Bcl-2 and Caspase-3 in age-related Purkinje cell death in murine organotypic culture: an in vitro model to study apoptosis

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12 December 2020

The effects of reduced climbing and parallel fibre input on Purkinje cell dendritic growth

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12 December 2020

Postnatal cerebellar cells of staggerer mutant mice express immature components on their surface

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12 December 2020

Transcriptional activation and repression by RORalpha, an orphan nuclear receptor required for cerebellar development

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12 December 2020

The harlequin mouse mutation downregulates apoptosis-inducing factor

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12 December 2020

10.1080/14734220600750184

Identifiers

DOI

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Dimensions Publication ID

14 August 2017

1046402086

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Fatcat ID

release_52s6xoxcmfec3jjhzuujy36tea

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Fatcat

https://api.fatcat.wiki/v0/release/52s6xoxcmfec3jjhzuujy36tea

24 November 2022

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