Prognostic role of p27Kip1 deregulation in colorectal cancer (Q36529936)

14 August 2017

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title

Prognostic role of p27Kip1 deregulation in colorectal cancer (English)

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14 August 2017

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Dan D Hershko

1

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PubMed ID

16826582

14 August 2017

Ma'anit Shapira

series ordinal

2

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PubMed ID

16826582

14 August 2017

language of work or name

English

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publication date

1 August 2006

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14 August 2017

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14 August 2017

107

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14 August 2017

4

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14 August 2017

668-675

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A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

14 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

New strategies for colorectal cancer prevention and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Molecular lesions in colorectal cancer: impact on prognosis? Original data and review of the literature

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

G1 control in mammalian cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer

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https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

p27 expression and gastric carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Cyclin-dependent kinase inhibitor p27(Kip1) is required for mouse mammary gland morphogenesis and function

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

https://api.crossref.org/works/10.1002%2FCNCR.22073

1 reference

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Prognostic value of p27, p53, and vascular endothelial growth factor in Dukes A and B colon cancer patients undergoing potentially curative surgery

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Determination of molecular marker expression can predict clinical outcome in colon carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Early invasive carcinoma in colonic polyps. A review of the literature with emphasis on the assessment of the risk of metastasis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Endoscopically removed malignant colorectal polyps: clinicopathologic correlations

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Proteasome-dependent degradation of p27/kip1 in gliomas.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Skp2 is oncogenic and overexpressed in human cancers

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

The expression of the ubiquitin ligase subunit Cks1 in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Therapeutic anti-cancer targets upstream of the proteasome.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

The ubiquitin-proteasome pathway and its role in cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.22073

7 January 2021

Identifiers

DOI

10.1002/CNCR.22073

1 reference

14 August 2017

1 reference

PubMed ID

16826582