Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb. (Q36546646)

14 August 2017

Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb. (English)

1 reference

14 August 2017

Debra T Chao

1

1 reference

14 August 2017

Mian Su

2

1 reference

14 August 2017

Sonia Tanlimco

3

1 reference

14 August 2017

Mien Sho

4

1 reference

14 August 2017

Donghee Choi

5

1 reference

14 August 2017

Mel Fox

6

1 reference

14 August 2017

Shiming Ye

7

1 reference

14 August 2017

Eric D Hsi

8

1 reference

14 August 2017

Lisa Durkin

9

1 reference

14 August 2017

Johnny Yin

10

1 reference

14 August 2017

Yongke Zhang

11

1 reference

14 August 2017

Han Kim

12

1 reference

14 August 2017

Gary C Starling

13

1 reference

14 August 2017

Patricia A Culp

14

1 reference

14 August 2017

17 October 2012

1 reference

Journal of Cancer Research and Clinical Oncology

14 August 2017

1 reference

14 August 2017

139

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14 August 2017

2

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14 August 2017

315-325

1 reference

https://scigraph.springernature.com/pub.10.1007/s00432-012-1332-x

14 August 2017

0 references

cites work

Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR.

1 reference

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Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis

30 September 2017

1 reference

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Evolving options for the treatment of metastatic breast cancer: progression-free survival as an endpoint

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Drug combination studies and their synergy quantification using the Chou-Talalay method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

30 September 2017

1 reference

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What's positive about 'triple-negative' breast cancer?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

TWEAK promotes ovarian cancer cell metastasis via NF-kappaB pathway activation and VEGF expression

30 September 2017

1 reference

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The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity

30 September 2017

1 reference

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The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting

30 September 2017

1 reference

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Triple-negative breast cancer: therapeutic options

30 September 2017

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

TWEAK induces liver progenitor cell proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Enhanced apoptosis and tumor regression induced by a direct agonist antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2.

30 September 2017

1 reference

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The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Dual role for TWEAK in angiogenic regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Multiple pathways of TWEAK-induced cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

TWEAK induces angiogenesis and proliferation of endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

Phase I study of safety and pharmacokinetics of a human anticytomegalovirus monoclonal antibody in allogeneic bone marrow transplant recipients

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549414

FGF-inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK.

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-012-1332-X

In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS00432-012-1332-X

Genetic alterations and oncogenic pathways associated with breast cancer subtypes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00432-012-1332-X

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23073510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23073510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23073510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00432-012-1332-X

1 reference

14 August 2017

1 reference

14 August 2017

1 reference