Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems. (Q36549101)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

review article

1 reference

title

Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Laura Masgrau Fontanet

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Kara E. Ranaghan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Adrian J Mulholland

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

10

Nigel S Scrutton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

3

Anna Roujeinikova

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Linus O Johannissen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Parvinder Hothi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Jaswir Basran

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

David Leys

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

1 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

Philosophical Transactions of the Royal Society B

27 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

1472

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

1375-1386

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Atomic description of an enzyme reaction dominated by proton tunneling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Modelling enzyme reaction mechanisms, specificity and catalysis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Ab initio quantum chemical and mixed quantum mechanics/molecular mechanics (QM/MM) methods for studying enzymatic catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Structural bases of hydrogen tunneling in enzymes: progress and puzzles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Enzymes: By chance, or by design?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Quantum-classical simulation methods for hydrogen transfer in enzymes: a case study of dihydrofolate reductase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Simulations of the large kinetic isotope effect and the temperature dependence of the hydrogen atom transfer in lipoxygenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

How enzymes work: analysis by modern rate theory and computer simulations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

A perspective on enzyme catalysis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

A compelling experimental test of the hypothesis that enzymes have evolved to enhance quantum mechanical tunneling in hydrogen transfer reactions: the beta-neopentylcobalamin system combined with prior adocobalamin data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Direct dynamics calculations of reaction rate and kinetic isotope effects in enzyme catalysed reactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Impact of enzyme motion on activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Barrier passage and protein dynamics in enzymatically catalyzed reactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

A new conceptual framework for enzyme catalysis. Hydrogen tunnelling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

The incorporation of quantum effects in enzyme kinetics modeling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Crystal structure of bacterial morphinone reductase and properties of the C191A mutant enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Quantum mechanical methods for enzyme kinetics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Boundary conditions for the Swain-Schaad relationship as a criterion for hydrogen tunneling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Network of coupled promoting motions in enzyme catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Hydride transfer in liver alcohol dehydrogenase: quantum dynamics, kinetic isotope effects, and role of enzyme motion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

30 September 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Hydrogen tunneling in biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Enzymatic H-transfer requires vibration-driven extreme tunneling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

A perspective on biological catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Electron transfer reactions between aromatic amine dehydrogenase and azurin.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Vibrationally enhanced tunneling as a mechanism for enzymatic hydrogen transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Deuterium kinetic isotope effect and stopped-flow kinetic studies of the quinoprotein methylamine dehydrogenase.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Evidence that both protium and deuterium undergo significant tunneling in the reaction catalyzed by bovine serum amine oxidase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Hydrogen tunneling in enzyme reactions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Reactions of benzylamines with methylamine dehydrogenase. Evidence for a carbanionic reaction intermediate and reaction mechanism similar to eukaryotic quinoproteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Three-dimensional structure of the quinoprotein methylamine dehydrogenase from Paracoccus denitrificans determined by molecular replacement at 2.8 A resolution

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Importance of barrier shape in enzyme-catalyzed reactions. Vibrationally assisted hydrogen tunneling in tryptophan tryptophylquinone-dependent amine dehydrogenases

28 June 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Deuterium isotope effects during carbon-hydrogen bond cleavage by trimethylamine dehydrogenase. Implications for mechanism and vibrationally assisted hydrogen tunneling in wild-type and mutant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

H-tunneling in the multiple H-transfers of the catalytic cycle of morphinone reductase and in the reductive half-reaction of the homologous pentaerythritol tetranitrate reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Identification of a protein-promoting vibration in the reaction catalyzed by horse liver alcohol dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

The low barrier hydrogen bond in enzymatic catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

The first experimental test of the hypothesis that enzymes have evolved to enhance hydrogen tunneling

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Dynamics of the dihydrofolate reductase-folate complex: catalytic sites and regions known to undergo conformational change exhibit diverse dynamical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Hydride transfer catalyzed by xylose isomerase: mechanism and quantum effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Proton-coupled electron transfer in soybean lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Hydrogen tunneling in the flavoenzyme monoamine oxidase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Evidence for environmentally coupled hydrogen tunneling during dihydrofolate reductase catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2006.1878

Dynamics of a flexible loop in dihydrofolate reductase from Escherichia coli and its implication for catalysis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1647315

Unusually large isotope effect for the reaction of aromatic amine dehydrogenase. A common feature of quinoproteins?

21 September 2018

1 reference

12 December 2020

Solvation, reorganization energy, and biological catalysis

1 reference

12 December 2020

Enzyme catalytic power minireview series

1 reference

12 December 2020

Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant

1 reference

12 December 2020

QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase

1 reference

12 December 2020

Kinetic studies of the mechanism of carbon-hydrogen bond breakage by the heterotetrameric sarcosine oxidase of Arthrobacter sp. 1-IN

1 reference

12 December 2020

Rate-promoting vibrations and coupled hydrogen-electron transfer reactions in the condensed phase: a model for enzymatic catalysis

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2006.1878

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16873125%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

PubMed publication ID

16873125

1 reference