MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy. (Q36552798)

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scientific article published on 17 December 2012

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English	MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy.	scientific article published on 17 December 2012

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scholarly article

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20 February 2020

MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy (English)

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20 February 2020

adaptive radiation therapy

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based on heuristic

inferred from title

immunohistochemistry

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based on heuristic

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Consolación Melguizo

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20 February 2020

José C. Prados

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20 February 2020

Roberto Madeddu

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20 February 2020

Gloria Perazzoli

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20 February 2020

Fernando Rodríguez-Serrano

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20 February 2020

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Beatriz González

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20 February 2020

Raul Ortiz

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20 February 2020

Angel Concha

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20 February 2020

Jaime Antonio Oliver

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20 February 2020

Rodrigo López

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20 February 2020

Antonia Aránega

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20 February 2020

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17 December 2012

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20 February 2020

Journal of Translational Medicine

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20 February 2020

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20 February 2020

250

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20 February 2020

Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma

1 reference

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30 September 2017

Recent advances in the molecular understanding of glioblastoma

1 reference

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30 September 2017

Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma

1 reference

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30 September 2017

O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation

1 reference

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30 September 2017

O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma

1 reference

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30 September 2017

The presence of stem cell marker-expressing cells is not prognostically significant in glioblastomas

1 reference

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30 September 2017

Quantitative digital assessment of MGMT immunohistochemical expression in glioblastoma tissue

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30 September 2017

Comprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBM

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30 September 2017

Current therapeutic paradigms in glioblastoma

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30 September 2017

O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications

1 reference

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30 September 2017

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

1 reference

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30 September 2017

The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas

1 reference

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30 September 2017

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy

1 reference

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30 September 2017

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients.

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Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma

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30 September 2017

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide

1 reference

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30 September 2017

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

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30 September 2017

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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30 September 2017

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

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30 September 2017

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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30 September 2017

Identification of a cancer stem cell in human brain tumors

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30 September 2017

Stem cells, cancer, and cancer stem cells

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Direct isolation of human central nervous system stem cells

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30 September 2017

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

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30 September 2017

Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.

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28 June 2018

MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma

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28 June 2018

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

1 reference

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27 July 2018

MGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution study.

1 reference

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21 September 2018

Pathological findings and prognostic factors in recurrent glioblastomas.

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21 September 2018

Clinical correlation of MGMT protein expression and promoter methylation in Chinese glioblastoma patients.

1 reference

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21 September 2018

Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide

1 reference

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O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma

1 reference

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1 reference

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21 September 2018

Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status

1 reference

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1 reference

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1 reference

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21 September 2018

Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas.

1 reference

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21 September 2018

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1 reference

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Stem cell marker CD133 affects clinical outcome in glioma patients.

1 reference

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MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities

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1 reference

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1 reference

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21 September 2018

MGMT immunohistochemical expression and promoter methylation in human glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23245659

12 December 2020

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10.1186/1479-5876-10-250

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20 February 2020

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