Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling (Q36556068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23086611%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling (English)

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16 February 2020

0 references

1 reference

6

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16 February 2020

Deborah A Cory-Slechta

4

object named as

Deborah A Cory-Slechta

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16 February 2020

author name string

Eric E Beier

1

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16 February 2020

Jason R Maher

2

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16 February 2020

Tzong-Jen Sheu

3

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16 February 2020

Andrew J Berger

5

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16 February 2020

J Edward Puzas

7

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16 February 2020

publication date

19 October 2012

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16 February 2020

number of pages

8

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Environmental Health Perspectives

inferred from page(s)

published in

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16 February 2020

volume

121

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16 February 2020

issue

1

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16 February 2020

page(s)

97-104

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Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis

16 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

The effect of lead on bone mineral properties from female adult C57/BL6 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Enhanced learning deficits in female rats following lifetime pb exposure combined with prenatal stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

A role for ethanol-induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/beta-catenin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Targeting the Wnt signaling pathway to augment bone formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Relationship of blood lead levels to incident nonspine fractures and falls in older women: the study of osteoporotic fractures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

The association between blood lead levels and osteoporosis among adults--results from the third national health and nutrition examination survey (NHANES III).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Chibby promotes adipocyte differentiation through inhibition of beta-catenin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Playing with bone and fat.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

LRP5 and Wnt signaling: a union made for bone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

PPARgamma1 synthesis and adipogenesis in C3H10T1/2 cells depends on S-phase progression, but does not require mitotic clonal expansion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Correlation of bone mineral density with strength and microstructural parameters of cortical bone in vitro.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Inhibition of adipogenesis by Wnt signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Linkage of a gene causing high bone mass to human chromosome 11 (11q12-13)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Lead toxicity: current concerns

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

National estimates of blood lead levels: United States, 1976-1980: association with selected demographic and socioeconomic factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Lead inhibits secretion of osteonectin/SPARC without significantly altering collagen or Hsp47 production in osteoblast-like ROS 17/2.8 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Effects of acute and chronic oval exposure of lead on blood pressure and bone mineral density in rats

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552813

Environmental toxicants may modulate osteoblast differentiation by a mechanism involving the aryl hydrocarbon receptor

21 September 2018

1 reference

12 December 2020

The effect of Pb(2+) on the structure and hydroxyapatite binding properties of osteocalcin

1 reference

12 December 2020

Osteon morphometry in females with femoral neck fractures

1 reference

12 December 2020

Regulation of osteoblastic gene expression by lead

1 reference

12 December 2020

Effect of lead on bone development and bone mass: a morphometric, densitometric, and histomorphometric study in growing rats

1 reference

12 December 2020

Osteopenia induced by long-term, low- and high-level exposure of the adult rat to lead

1 reference

12 December 2020

Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.1205374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23086611%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

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16 February 2020

PubMed publication ID

23086611

1 reference

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