Muscle-specific vascular endothelial growth factor deletion induces muscle capillary rarefaction creating muscle insulin resistance (Q36560546)

14 August 2017

Muscle-specific vascular endothelial growth factor deletion induces muscle capillary rarefaction creating muscle insulin resistance (English)

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14 August 2017

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Jeffrey S Bonner

1

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14 August 2017

Louise Lantier

2

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14 August 2017

Clinton M Hasenour

3

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14 August 2017

Freyja D James

4

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14 August 2017

Deanna P Bracy

5

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14 August 2017

David H Wasserman

6

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14 August 2017

language of work or name

English

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publication date

21 September 2012

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14 August 2017

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14 August 2017

62

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14 August 2017

2

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14 August 2017

572-580

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

14 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3554359/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo

30 September 2017

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Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature

30 September 2017

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Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2

30 September 2017

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Progressive hyperglycemia across the glucose tolerance continuum in older obese adults is related to skeletal muscle capillarization and nitric oxide bioavailability.

30 September 2017

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Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice

30 September 2017

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30 September 2017

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Autocrine VEGF signaling is required for vascular homeostasis

30 September 2017

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Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

30 September 2017

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30 September 2017

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Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers

30 September 2017

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Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo

30 September 2017

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Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

30 September 2017

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Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

30 September 2017

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A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function

30 September 2017

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30 September 2017

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Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

30 September 2017

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

30 September 2017

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

30 September 2017

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Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

30 September 2017

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Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance

30 September 2017

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30 September 2017

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An improved procedure for the assay of glycogen synthase and phosphorylase in rat liver homogenates

30 September 2017

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Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice

30 September 2017

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Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

28 June 2018

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Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice

28 June 2018

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Tissue-specific distribution and developmental regulation of M and B creatine kinase mRNAs

28 June 2018

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Direct administration of insulin into skeletal muscle reveals that the transport of insulin across the capillary endothelium limits the time course of insulin to activate glucose disposal

28 June 2018

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Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.

21 September 2018

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Reduced expression of vascular endothelial growth factor paralleled with the increased angiostatin expression resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in human type 2 diabetic arterial vasculature.

21 September 2018

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Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake

21 September 2018

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Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse

21 September 2018

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Increased collagen content in insulin-resistant skeletal muscle

21 September 2018

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Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease.

21 September 2018

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Hypertension-independent microvascular rarefaction in the obese Zucker rat model of the metabolic syndrome

21 September 2018

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Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishme

21 September 2018

1 reference

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Decreased muscle capillary permeability surface area in type 2 diabetic subjects

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Capillary regression in vascular endothelial growth factor-deficient skeletal muscle.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Measurement of size and turnover rate of body glucose pool by the isotope dilution method

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Delayed transcapillary transport of insulin to muscle interstitial fluid in obese subjects

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Active and passive capillary control in red muscle at rest and in exercise.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Microvascular blood flow distribution in skeletal muscle. An intravital microscopic study in the rabbit.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Mechanism of insulin resistance in insulin-dependent diabetes mellitus: a major role for reduced skeletal muscle blood flow

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554359

Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans

21 September 2018

1 reference

12 December 2020

Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1

1 reference

12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

1 reference

12 December 2020

Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment

1 reference

12 December 2020

Limitations to basal and insulin-stimulated skeletal muscle glucose uptake in the high-fat-fed rat

1 reference

12 December 2020

Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue

1 reference

12 December 2020

A rapid method for the determination of glycogen content and radioactivity in small quantities of tissue or isolated hepatocytes

1 reference

12 December 2020

Effects of chronic elevation in plasma cortisol on hepatic carbohydrate metabolism

1 reference

12 December 2020

Muscle fiber composition and capillary density in women and men with NIDDM

1 reference

12 December 2020

VEGF is required for growth and survival in neonatal mice

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB12-0354

1 reference

14 August 2017

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14 August 2017

PubMed publication ID

23002035

1 reference