The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. (Q36564303)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

title

The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state (English)

1 reference

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21 October 2019

3

1 reference

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21 October 2019

author name string

E J Smith

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

G Leone

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

L Jakoi

4

1 reference

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21 October 2019

J R Nevins

5

1 reference

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21 October 2019

language of work or name

English

0 references

publication date

1 December 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

21 October 2019

published in

1 reference

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21 October 2019

volume

16

1 reference

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21 October 2019

issue

12

1 reference

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21 October 2019

page(s)

6965-6976

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

The retinoblastoma protein as a transcriptional repressor

21 October 2019

cites work

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p21 Disrupts the interaction between cdk2 and the E2F-p130 complex

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Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

30 September 2017

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The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB

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Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

30 September 2017

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Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection

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Expression of transcription factor E2F1 induces quiescent cells to enter S phase

30 September 2017

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Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain

30 September 2017

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Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

30 September 2017

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An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription

30 September 2017

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Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F.

30 September 2017

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Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

30 September 2017

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Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation

30 September 2017

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30 September 2017

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Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

30 September 2017

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The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E

30 September 2017

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30 September 2017

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DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control

30 September 2017

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30 September 2017

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30 September 2017

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

30 September 2017

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Multiple change in E2F function and regulation occur upon muscle differentiation

30 September 2017

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E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

30 September 2017

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Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression

30 September 2017

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The transcription factor E2F-1 is a downstream target of RB action

30 September 2017

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30 September 2017

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30 September 2017

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Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Regulation of E2F-1 gene expression by p130 (Rb2) and D-type cyclin kinase activity

30 September 2017

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The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

30 September 2017

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The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

30 September 2017

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Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

30 September 2017

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The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

30 September 2017

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The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

30 September 2017

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Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

30 September 2017

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The retinoblastoma protein is phosphorylated on multiple sites by human cdc2

30 September 2017

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The retinoblastoma protein physically associates with the human cdc2 kinase

30 September 2017

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The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

30 September 2017

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30 September 2017

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Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein

30 September 2017

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Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding

30 September 2017

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E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

30 September 2017

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Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

30 September 2017

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

30 September 2017

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Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

30 September 2017

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Shared role of the pRB-related p130 and p107 proteins in limb development

30 September 2017

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The cdk2 kinase is required for the G1-to-S transition in mammalian cells.

28 June 2018

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28 June 2018

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Cell cycle-specific association of E2F with the p130 E1A-binding protein

28 June 2018

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Mechanism of active transcriptional repression by the retinoblastoma protein

28 June 2018

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Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

28 June 2018

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Expression of c-jun during macrophage differentiation of HL-60 cells

28 June 2018

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Identification of a growth suppression domain within the retinoblastoma gene product

28 June 2018

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The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

28 June 2018

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Retinoblastoma protein switches the E2F site from positive to negative element

28 June 2018

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A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

28 June 2018

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Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.

28 June 2018

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Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

21 September 2018

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Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

21 September 2018

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12 December 2020

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein

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E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity

1 reference

12 December 2020

Expression and activity of the retinoblastoma protein (pRB)-family proteins, p107 and p130, during L6 myoblast differentiation

1 reference

12 December 2020

Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.16.12.6965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8943352%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference