Plasmin deficiency in Alzheimer's disease brains: causal or casual? (Q36565614)

15 August 2017

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title

Plasmin deficiency in Alzheimer's disease brains: causal or casual? (English)

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15 August 2017

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Carlos G Dotti

1

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PubMed ID

16908991

15 August 2017

Cristian Galvan

series ordinal

2

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PubMed ID

16908991

15 August 2017

Maria Dolores Ledesma

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3

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15 August 2017

1 January 2004

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Neurodegenerative Diseases

15 August 2017

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15 August 2017

1

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15 August 2017

4-5

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15 August 2017

205-212

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Mutant genes in familial Alzheimer's disease and transgenic models

15 August 2017

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Alzheimer's disease and Abeta toxicity: from top to bottom

21 January 2018

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

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Statins and the risk of dementia

21 January 2018

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

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Clearing the brain's amyloid cobwebs

21 January 2018

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Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

21 January 2018

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

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Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains

21 January 2018

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The metallobiology of Alzheimer's disease

21 January 2018

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Tissue plasminogen activator expression in the embryonic nervous system

21 January 2018

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Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice

21 January 2018

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Tissue plasminogen activator controls multiple forms of synaptic plasticity and memory

21 January 2018

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Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice.

21 January 2018

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The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate

21 January 2018

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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

21 January 2018

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Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation

21 January 2018

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Neuronal cell death and tPA.

21 January 2018

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Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin.

21 January 2018

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

21 January 2018

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Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains

21 January 2018

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Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen.

21 January 2018

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Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

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RSH/Smith-Lemli-Opitz syndrome: a multiple congenital anomaly/mental retardation syndrome due to an inborn error of cholesterol biosynthesis

21 January 2018

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Seladin-1 transcription is linked to neuronal degeneration in Alzheimer's disease

21 January 2018

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Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice

21 January 2018

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Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons

21 January 2018

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Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

1 reference

APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress

21 January 2018

1 reference

21 January 2018

Identifiers

0 references

1 reference

PubMed ID

16908991