A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. (Q36569558)

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scientific article published on August 1997

Language	Label	Description	Also known as
English	A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization.	scientific article published on August 1997

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scholarly article

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5 November 2019

A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization (English)

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5 November 2019

Jan Krzysztof Blusztajn

7

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5 November 2019

author name string

H Li

1

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S E Leeman

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B E Slack

3

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5 November 2019

G Hauser

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5 November 2019

W S Saltsman

5

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J E Krause

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5 November 2019

N D Boyd

8

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publication date

1 August 1997

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5 November 2019

Proceedings of the National Academy of Sciences of the United States of America

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94

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17

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9475-9480

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5 November 2019

Desensitization of the neurokinin 1 receptor is mediated by the receptor carboxy-terminal region, but is not caused by receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23228

30 September 2017

Desensitization of G protein-coupled receptors

1 reference

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30 September 2017

Inositol trisphosphate and calcium signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23228

30 September 2017

Calcium signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23228

30 September 2017

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

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30 September 2017

Neurotransmitter functions of mammalian tachykinins

1 reference

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30 September 2017

Inositol trisphosphate and calcium signaling

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Regulation of G protein-coupled receptors by receptor kinases and arrestins.

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Inositol trisphosphate and diacylglycerol as second messengers

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

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30 September 2017

Molecular characterization of a functional cDNA for rat substance P receptor

1 reference

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30 September 2017

Molecular characterization of a functional cDNA encoding the rat substance P receptor

1 reference

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30 September 2017

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

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30 September 2017

Role of Inositol Phosphates in the Actions of Substance P on NK1Receptors in Exocrine Gl and Cells

1 reference

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30 September 2017

Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor

1 reference

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30 September 2017

Homologous desensitization of substance-P-induced inositol polyphosphate formation in rat parotid acinar cells

1 reference

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28 June 2018

SK&F 96365, a novel inhibitor of receptor-mediated calcium entry

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28 June 2018

Different modes of regulation for receptors activating phospholipase C in the rat pancreatoma cell line AR4-2J

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28 June 2018

Calcium-independent effects of TMB-8. Modification of phospholipid metabolism in neuroblastoma cells by inhibition of choline uptake

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28 June 2018

Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells

1 reference

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28 June 2018

Ligand Binding Kinetics of Substance P and Neurokinin A Receptors Stably Expressed in Chinese Hamster Ovary Cells and Evidence for Differential Stimulation of Inositol 1,4,5‐Trisphosphate and Cyclic AMP Second Messenger Responses

1 reference

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28 June 2018

Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor

1 reference

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21 September 2018

Mechanisms of desensitization and resensitization of G protein-coupled neurokinin1 and neurokinin2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23228

21 September 2018

The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate.

1 reference

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21 September 2018

Attenuation of agonist-induced desensitization of the rat substance P receptor by progressive truncation of the C-terminus

1 reference

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21 September 2018

Characterization of the Substance P (NK-1) Receptor in Tunicamycin-Treated Transfected Cells Using a Photoaffinity Analogue of Substance P

1 reference

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12 December 2020

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Chemical cross-linking of the substance P (NK-1) receptor to the alpha subunits of the G proteins Gq and G11

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

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Substance P receptor on parotid cell membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A guanine nucleotide-dependent regulatory protein couples substance P receptors to phospholipase C in rat parotid gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid desensitization of substance P- but not carbachol-induced increases in inositol trisphosphate and intracellular Ca++ in rat parotid acinar cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor-mediated synthesis of prostaglandins in rat Kupffer cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical Characterization of Two Different Forms of the Substance P Receptor in Rat Submaxillary Gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional nonequivalence of structurally homologous domains of neurokinin-1 and neurokinin-2 type tachykinin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

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Role of intracellular calcium and protein kinases in the activation of hepatic Na+/taurocholate cotransport by cyclic AMP

1 reference

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12 December 2020

based on heuristic

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Substance P-induced elevation of intracellular calcium in transfected Chinese hamster ovary cells: role of inositol trisphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the substance P receptor-mediated calcium influx in cDNA transfected Chinese hamster ovary cells. A possible role of inositol 1,4,5-trisphosphate in calcium influx

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity labeling the substance P receptor using a derivative of substance P containing p-benzoylphenylalanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9256507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.94.17.9475

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5 November 2019

1997PNAS...94.9475L

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1 reference

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5 November 2019

1 reference

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5 November 2019

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