Mechanisms of disease: Fibroblasts--a new look at an old problem (Q36577128)

15 August 2017

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title

Mechanisms of disease: Fibroblasts--a new look at an old problem (English)

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15 August 2017

Eric G Neilson

1

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15 August 2017

1 February 2006

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Nature Clinical Practice Nephrology

15 August 2017

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15 August 2017

2

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15 August 2017

101-108

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15 August 2017

2

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Mechanisms of tubulointerstitial fibrosis

15 August 2017

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

New insights into mechanisms of fibrosis in immune renal injury

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Conditional abatement of tissue fibrosis using nucleoside analogs to selectively corrupt DNA replication in transgenic fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Epithelial-mesenchymal transition and its implications for fibrosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Mesenchymal to epithelial conversion in rat metanephros is induced by LIF.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

The renal papilla is a niche for adult kidney stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Identification and characterization of a fibroblast marker: FSP1

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Evidence that fibroblasts derive from epithelium during tissue fibrosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

The role of epithelial-to-mesenchymal transition in renal fibrosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Integrative nuclear FGFR1 signaling (INFS) as a part of a universal “feed‐forward‐and‐gate” signaling module that controls cell growth and differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

The snail superfamily of zinc-finger transcription factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Regulation of PDGF and its receptors in fibrotic diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Podocyte is the major culprit accounting for the progression of chronic renal disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Remission of renal disease: recounting the challenge, acquiring the goal

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Pathophysiology of disease progression in proteinuric nephropathies

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Proteinuria and growth factors in the development of tubulointerstitial injury and scarring in kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kappa B activation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Albuminuria and renal injury--beware of proteins bearing gifts.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Glomerular ultrafiltration and apical tubular action of IGF-I, TGF-beta, and HGF in nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Combination therapy with ACE inhibitors and angiotensin II receptor blockers to halt progression of chronic renal disease: pathophysiology and indications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Role of angiotensin II in tubulointerstitial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Chemokines and chemokine receptors are involved in the resolution or progression of renal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Angiotensin-converting enzyme inhibition and renal protection in nondiabetic patients: the data of the meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

A comparison of iothalamate-GFR and serum creatinine-based outcomes: acceleration in the rate of GFR decline in the African American Study of Kidney Disease and Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

PDGF receptor kinase inhibitors for the treatment of PDGF driven diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Angiotensin II and renal fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Potential methods to prevent interstitial fibrosis in renal disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Protein traffic activates NF-kB gene signaling and promotes MCP-1–dependent interstitial inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

Signals which build a tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Peripheral blood fibrocytes: differentiation pathway and migration to wound sites

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Setting a trap for tissue fibrosis

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https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

The return of glomerular-filtered albumin to the rat renal vein

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Tubular catabolism of albumin is associated with the release of an inflammatory lipid

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Cytokines and cell cycle regulation in the fibrous progression of crescent formation in antiglomerular basement membrane nephritis of WKY rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEPH0093

7 January 2021

Identifiers

DOI

10.1038/NCPNEPH0093

1 reference

15 August 2017

1 reference

PubMed ID

16932401