RB, the conductor that orchestrates life, death and differentiation (Q36579239)

15 August 2017

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title

RB, the conductor that orchestrates life, death and differentiation (English)

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15 August 2017

Khidr L

1

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15 August 2017

Chen PL

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 August 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

38

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15 August 2017

5210-5219

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209612

15 August 2017

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cites work

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Genetic origin of mutations predisposing to retinoblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Acetylation control of the retinoblastoma tumour-suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Requirement for a functional Rb-1 gene in murine development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma tumour suppressor in development and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Opposing roles of pRB and p107 in adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Pocket proteins and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb -deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The search for the retinoblastoma cell of origin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

EID-2, a novel member of the EID family of p300-binding proteins inhibits transactivation by MyoD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Selective ablation of retinoblastoma protein function by the RET finger protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cyclin-dependent kinase control of centrosome duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F4 loss suppresses tumorigenesis in Rb mutant mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb interacts with histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A novel Rb- and p300-binding protein inhibits transactivation by MyoD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Cell cycle targets of the DNA tumor viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Acetylation regulates the differentiation-specific functions of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A Restriction Point for Control of Normal Animal Cell Proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Identification of a 60-kilodalton Rb-binding protein, RBP60, that allows the Rb-E2F complex to bind DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The retinoblastoma protein: more than a tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A novel E1A domain mediates skeletal-muscle-specific enhancer repression independently of pRB and p300 binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Regulation of RNA polymerase III transcription during cell cycle entry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

1 reference

7 January 2021

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

A critical temporal requirement for the retinoblastoma protein family during neuronal determination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

RB kinases and RB-binding proteins: new points of view

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Sibling rivalry in the E2F family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Target gene specificity of E2F and pocket protein family members in living cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

The identification of E2F1-specific target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Retinoblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Extra-embryonic function of Rb is essential for embryonic development and viability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb-mediated chromatin structure regulation and transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Rb regulates proliferation and rod photoreceptor development in the mouse retina

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209612

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209612

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference